Do You Get Sick More Without Tonsils?

The palatine tonsils are paired masses of lymphatic tissue located at the back of the throat, serving as a first line of immune defense against pathogens entering through the mouth and nose. Their removal, known as a tonsillectomy, is a common surgical procedure that often leads people to question whether the body is left vulnerable to illness afterward. This concern stems from the assumption that removing a part of the immune system must inherently weaken it. To address this worry, an examination of the tonsils’ function, the reasons for their removal, and the long-term data on post-surgery health is necessary.

How Tonsils Function in the Immune System

The tonsils are strategically positioned as immunological sentinels at the entrance of the aerodigestive tract, forming a protective ring of tissue known as Waldeyer’s ring. Classified as secondary lymphoid tissue, they house a dense concentration of immune cells, including B and T lymphocytes. The tonsils feature deep folds, called crypts, which increase the surface area available to intercept inhaled and ingested foreign particles and microbes.

This structure allows the tonsils to actively sample antigens from the environment, acting as an immune surveillance system. Specialized M cells capture antigens and pass them to the underlying immune cells. This process initiates the adaptive immune response, leading to the production of antibodies like Immunoglobulin A (IgA) and Immunoglobulin G (IgG), which helps the body develop immune memory.

Primary Reasons for Tonsillectomy

Tonsillectomy is typically reserved for cases where the tonsils become a liability to health rather than an asset for immune function. The two primary medical indications for the procedure are recurrent throat infections and mechanical obstruction of the airway. Recurrent tonsillitis often means a patient experiences seven or more documented episodes in the preceding year, five or more per year for two consecutive years, or three or more per year for three consecutive years. In these instances, the tonsils are chronically inflamed and harbor infection, making the patient repeatedly ill.

The second major indication is obstructive sleep-disordered breathing, most commonly obstructive sleep apnea (OSA). Enlarged tonsils and adenoids can physically block the upper airway during sleep, leading to snoring, disrupted sleep, and health issues. The tonsil tissue is removed because its physical size causes a detrimental health outcome, regardless of its immune function. The decision to remove the tonsils is made when the harm caused by their disease or size outweighs their local immune benefit.

Long-Term Impacts on Illness Frequency

For patients who undergo tonsillectomy due to recurrent throat infections, studies consistently show a significant reduction in the frequency and severity of sore throat episodes. For example, one study of adults showed the mean number of annual sore throat episodes decreased dramatically from about ten before surgery to only two afterward. This confirms that the procedure is highly effective at treating the specific problem it is intended to solve.

However, the question of long-term risk for other, non-throat-specific infections is complex. A large population-based study suggested that childhood tonsillectomy may be associated with a slightly increased long-term risk for certain respiratory, infectious, and allergic diseases. This study estimated a two to three times greater risk of upper respiratory tract diseases over a period of up to 30 years.

Interpretation of this data requires acknowledging that large cohort studies often face challenges like confounding and selection bias. Critics point out that children requiring tonsillectomy are already predisposed to respiratory issues, making it difficult to isolate the surgery as the cause of later illness. Other studies analyzing long-term complications found that the rate of increased infections was low, suggesting the risk may be limited to specific patient groups. For most people, a tonsillectomy does not lead to a noticeable increase in common colds or flu.

The Body’s Compensatory Immune Mechanisms

The body does not suffer an immune collapse after tonsil removal because the immune system operates with a high degree of redundancy. The removal of the palatine tonsils only takes out one set of organs from a larger, interconnected defense network. The rest of Waldeyer’s ring remains intact to take over the local immune surveillance role.

This ring includes the pharyngeal tonsils (adenoids) and the lingual tonsils, situated at the base of the tongue. These surrounding lymphoid tissues are capable of compensating for the loss of the palatine tonsils by increasing their own activity and size, a process known as compensatory hypertrophy. They continue to sample antigens and produce mucosal antibodies, maintaining the local immune barrier.

Beyond Waldeyer’s ring, the systemic immune system provides the main defense against illness. This system includes the vast network of lymph nodes, the spleen, and the bone marrow, which are the primary sites for generating and circulating immune cells. The comprehensive function of the systemic immune system remains unaffected by the removal of the two palatine tonsils, allowing the body to retain its full capacity to fight off most common respiratory viruses and bacteria.