Do Humans Have a Jacobson’s Organ (Vomeronasal Organ)?

Many animals possess specialized sensory organs, like the Jacobson’s organ, to detect subtle chemical cues. This raises a common question: Do humans have a similar organ?

What is the Jacobson’s Organ?

The Jacobson’s organ, also known as the vomeronasal organ (VNO), is a specialized chemosensory organ found in a wide range of animals, including many mammals, reptiles, and amphibians. Located in the nasal cavity or roof of the mouth, it is designed to detect specific non-volatile chemical signals, often referred to as pheromones. These chemical messages convey information between members of the same species, influencing behaviors such as mating, territorial marking, and social recognition.

In snakes and lizards, for instance, the VNO is highly developed; they use their forked tongues to collect scent molecules and deliver them directly to the organ for analysis. Many mammals, including cats, dogs, and pigs, also possess a functional VNO that contributes to their social and reproductive behaviors, sometimes involving a distinctive “Flehmen response” to draw chemicals into the organ. The VNO’s sensory neurons project to a distinct brain region called the accessory olfactory bulb, which processes this specialized chemical information.

The Human Vomeronasal Organ: Presence and Development

A structure resembling the vomeronasal organ is present during human embryonic and fetal development. It forms as a tubular VNO early in development and is homologous to the VNOs found in other mammals.

While the human VNO develops prenatally, its fate in adult humans differs significantly from many other species. Histological studies show that a tubular structure, typically 2 to 10 millimeters long, can be identified in the nasal septum of most adult humans. However, its macroscopic visibility varies greatly among individuals, and it is more commonly observed in children.

Vestigial Structure or Functional Remnant?

Despite its presence during development and in adults, the human vomeronasal organ is widely considered a vestigial structure. This means it’s an anatomical feature inherited from an ancestor that has lost much or all of its original function.

The scientific consensus is that the human VNO is non-functional. In adults, it lacks the specialized sensory neurons and nerve fibers for chemical detection. Humans also lack an accessory olfactory bulb, the brain region that processes VNO signals in other animals. Furthermore, the genes for VNO receptor proteins in humans are non-functional due to mutations.

Alternative Chemical Sensing in Humans

While the vomeronasal organ is not considered functional for chemical communication in humans, we possess sophisticated alternative systems for perceiving and responding to chemical signals from our environment and other individuals. The primary mechanism is the main olfactory system, our sense of smell. This system detects volatile chemical compounds, playing a significant role in our perception of the world and our social interactions.

Human olfaction contributes to subtle social cues, influencing emotional states and even factors related to mate choice. Beyond smell, the trigeminal system, also known as the common chemical sense, detects general chemical irritation. This system responds to substances like menthol, which feels cool, or capsaicin, which creates a burning sensation. Both the olfactory and trigeminal systems work in concert, providing humans with a comprehensive range of chemical sensing abilities.