Do Glycerin Suppositories Expire?

Glycerin suppositories are a common, over-the-counter medication used for quick relief from occasional constipation. They are classified as hyperosmotic laxatives, working by drawing water into the lower bowel. This influx of water softens the stool, making it easier to pass. The suppository base melts at body temperature, releasing the glycerin to stimulate a bowel movement.

Understanding Expiration Dates

Glycerin suppositories do expire, and the date printed on the packaging is the manufacturer’s guarantee. This date signifies the period during which the product maintains its potency, stability, and quality when stored correctly. Manufacturers determine this date based on stability testing, ensuring the components remain effective and safe until that specified point. After the printed date, the manufacturer can no longer ensure the suppository contains the labeled amount of active ingredient or that it will perform as intended. Regulatory bodies recommend disposing of the product once the expiration date has been reached.

How Suppositories Change Over Time

The physical integrity of the suppository depends on its non-glycerin base, typically a matrix of gelatin or a wax-like substance. Glycerin is highly hygroscopic, readily absorbing moisture from the environment. This tendency causes changes in the suppository’s texture under poor storage conditions. High humidity can make the suppository overly soft or mushy. Conversely, moisture loss in a dry environment leads to a hardened, brittle, or crystallized texture. These physical changes prevent the suppository from properly melting or dissolving once inserted.

Potential Issues with Usage

Using a physically degraded suppository can lead to diminished efficacy and increased discomfort. If the suppository has hardened or crystallized, it may not melt completely at body temperature to release the glycerin and initiate the laxative effect. A failure to melt significantly reduces the osmotic action, leading to ineffective treatment. Furthermore, a brittle or hardened suppository can cause physical irritation or discomfort during and after insertion. The integrity of compromised packaging also introduces a low risk of microbial contamination.

Storing for Best Results

Proper storage is necessary to ensure the suppository remains effective up to its expiration date. The product should be kept in a cool, dry place, ideally at room temperature, between 68°F and 77°F (20°C and 25°C). Keep suppositories away from excessive heat, which can cause them to soften or melt prematurely. High humidity should also be avoided, as it compromises the suppository’s structure.

Disposal Guidelines

If a product has expired or is no longer needed, it should not be flushed down the toilet. Consumers should follow local guidelines for disposal, such as using a medication take-back program. Another option is mixing the product with an undesirable substance like dirt or used coffee grounds before placing it in the trash.