Desonide cream is a prescription low-potency topical corticosteroid. Healthcare providers prescribe it to alleviate inflammation, itching, and redness from skin conditions like eczema and dermatitis. It reduces the body’s inflammatory response in the skin and is applied directly to affected skin areas.
Common Localized Skin Reactions
Localized skin reactions may occur at the application site. These effects are generally mild and often temporary, diminishing as the skin adjusts. Common reactions include burning or stinging sensations when first applied.
Other common side effects include irritation, redness, and dryness. Some users might also notice peeling or a feeling of tightness. Occasionally, folliculitis (inflammation of hair follicles) may develop. If these symptoms persist or worsen, consult a healthcare provider.
Less Common and Systemic Effects
While desonide cream is a low-potency corticosteroid, prolonged or extensive use can lead to less common, yet potentially more significant, side effects. One such effect is skin thinning (atrophy), which can make the skin more susceptible to bruising and tearing. Stretch marks (striae) are also possible, especially in areas where the skin is repeatedly stretched.
Changes in skin pigmentation, appearing as either lightening or darkening, can occur. Acne-like eruptions or increased hair growth may also occur in applied regions. Systemic absorption, where the medication enters the bloodstream, is rare with appropriate use of low-potency steroids, but can lead to more widespread effects.
In rare instances, particularly with high doses, prolonged use, or application over large body surface areas, systemic effects such as Cushing’s syndrome or adrenal suppression may manifest. Cushing’s syndrome can involve symptoms like a rounded face, weight gain, and easy bruising. Adrenal suppression may lead to fatigue and muscle weakness. If desonide is applied near the eyes, there is a rare risk of blurred vision or glaucoma. Children are at a higher risk for systemic effects, including slowed growth and delayed weight gain, due to their larger skin surface area to body mass ratio.
Important Usage Considerations
Adhering to proper usage guidelines for desonide cream is important to minimize side effect risks. The medication should not be used for prolonged periods; typically, cream, lotion, or ointment formulations are prescribed for up to two weeks, while gel and foam may be used for up to four weeks. Applying the cream over large body areas should also be avoided, as this increases the potential for systemic absorption.
Desonide cream should not be applied to broken, damaged, or infected skin unless directed by a healthcare provider. Using occlusive dressings (e.g., bandages, tight-fitting diapers) over treated areas can increase absorption and side effect risk. When using desonide on sensitive areas like the face, armpits, or groin, exercise caution, as these regions are more prone to adverse reactions. Always consult a healthcare provider for specific instructions, especially for children, where dosage and duration require careful consideration.
Recognizing Serious Reactions and When to Seek Help
It is important to recognize when a side effect of desonide cream warrants medical attention. If common localized reactions, such as burning, itching, or redness, persist or worsen, discontinue the medication and contact your healthcare provider. Signs of less common or systemic effects, including unusual weight gain, persistent fatigue, easy bruising, or changes in vision, should also prompt immediate medical consultation.
Seek urgent medical care for symptoms of a severe allergic reaction. These can include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If the skin condition does not improve within two to four weeks of consistent use, or if it noticeably deteriorates, a reassessment by a healthcare professional is necessary.