Can You Overdose on Steroids? Signs and Risks

Steroids are powerful substances used medically, but they carry significant risks when misused. This article clarifies what an “overdose” entails for different types of steroids and explores the associated health risks.

Understanding Steroid Types and Overdose Risk

The term “steroid” refers to two primary categories: anabolic-androgenic steroids (AAS) and corticosteroids. AAS are synthetic variations of the male hormone testosterone, used to promote muscle growth and enhance athletic performance. An “overdose” with AAS is typically not an acute, single-dose event causing immediate death, but rather a consequence of chronic, high-dose misuse over time. While acute overdose is rare, extremely high doses or impure substances can lead to severe issues.

Corticosteroids, such as prednisone or hydrocortisone, are used medically to reduce inflammation and suppress the immune system, treating conditions like asthma. For corticosteroids, an acute, life-threatening overdose from a single large dose is uncommon. Instead, the primary concern arises from prolonged high doses or sudden cessation of the medication, which can lead to serious adverse effects. For both types of steroids, the most significant health concerns stem from the cumulative, damaging effects of chronic excessive use or misuse, rather than a singular lethal event.

Signs of Excessive Steroid Use

Excessive steroid use manifests through various physical and psychological changes. For anabolic-androgenic steroids, individuals might experience rapid muscle gain, significant alterations in body composition, severe acne, hair loss, and male breast tissue (gynecomastia). Women using AAS may notice a deepened voice, increased facial and body hair, and reduced breast size. Psychologically, mood swings, increased aggression (often referred to as “roid rage”), irritability, and paranoia are common.

Excessive corticosteroid use, particularly through prolonged medical prescriptions, presents a different set of signs. Physical symptoms include fluid retention, noticeable weight gain (especially in the face and trunk), and high blood pressure. Individuals may also experience elevated blood sugar levels, sleep disturbances, and a rounder face (“moon face”). Mood changes, such as anxiety, depression, and general restlessness, are also observed.

Long-Term Health Impacts of Steroid Misuse

Prolonged misuse of anabolic-androgenic steroids can lead to serious, lasting health consequences. Cardiovascular problems are a significant concern, including damage to the heart muscle, increased risk of heart attack and stroke, high cholesterol, and elevated blood pressure. Liver damage, ranging from abnormal function to the development of tumors, and kidney problems can occur. Reproductive issues are common, such as testicular atrophy and infertility in men, and menstrual irregularities and reduced fertility in women. Psychiatric effects can persist, including severe depression, anxiety, and suicidal thoughts.

For corticosteroids, prolonged high-dose use also carries a range of chronic health impacts. Individuals face an increased risk of infections due to immune suppression. Bone weakening, known as osteoporosis, which increases fracture risk, is a common long-term effect. Eye conditions such as cataracts and glaucoma may develop.

Prolonged corticosteroid use can also lead to adrenal suppression, where the body’s natural cortisol production is reduced, potentially resulting in an adrenal crisis if the medication is stopped suddenly. Existing conditions like diabetes or hypertension may worsen.

When to Seek Immediate Medical Attention

Prompt medical attention is necessary if someone exhibits severe or life-threatening symptoms related to steroid use or misuse. This includes instances where an individual has taken an extremely large, acute dose of any steroid and is experiencing severe chest pain, difficulty breathing, seizures, or loss of consciousness. These symptoms indicate a medical emergency.

If someone using steroids experiences severe psychological distress, such as suicidal thoughts, extreme paranoia, or psychosis, urgent professional help is crucial. For individuals on corticosteroids, sudden and severe symptoms after discontinuing their medication, such as profound weakness, confusion, or severe abdominal pain, could signal an adrenal crisis. In these situations, call emergency services or a poison control center immediately. Providing complete and honest information to medical professionals is essential for effective treatment.