Can You Have GERD and Not Know It?

Gastroesophageal Reflux Disease (GERD) is a chronic condition defined by the frequent backflow of stomach contents, including acid, into the esophagus. This movement happens when the lower esophageal sphincter, the muscular valve between the esophagus and stomach, relaxes inappropriately. While this process typically creates the classic symptoms of heartburn and acid regurgitation, many individuals experience reflux without that familiar burning sensation. The answer to whether you can have GERD and not know it is yes, as not all cases present with typical, obvious indicators.

Understanding Asymptomatic and Atypical GERD

Reflux that causes damage or symptoms without the presence of heartburn is categorized as either asymptomatic or atypical GERD. Asymptomatic GERD, sometimes referred to as “silent GERD,” involves measurable damage to the esophagus, such as inflammation, without any noticeable symptoms. Studies have shown that a significant percentage of patients with visible esophageal damage report no classic symptoms.

More common is atypical GERD, where the symptoms are present but manifest outside of the esophagus, often involving the throat, voice box, or lungs. This is frequently termed Laryngopharyngeal Reflux (LPR) or “silent reflux,” because the stomach contents travel much higher, reaching the upper respiratory tract. The tissues in the throat and larynx are far more sensitive to acid and even non-acidic reflux material than the esophagus lining.

This high-reaching reflux can cause a persistent, chronic cough, which is a common atypical presentation. Other symptoms include hoarseness or laryngitis, a frequent need to clear the throat, and the sensation of having a lump in the throat (globus sensation). Non-cardiac chest pain and difficulty swallowing (dysphagia) are also recognized atypical signs of GERD. These varied and non-specific symptoms can easily be misattributed to allergies or other unrelated conditions.

The Health Risks of Undiagnosed Reflux

Allowing chronic reflux, whether silent or atypical, to continue untreated poses several serious long-term health risks. The constant exposure of the esophageal lining to stomach acid can lead to inflammation, a condition known as esophagitis. Chronic esophagitis can sometimes cause bleeding and iron-deficiency anemia due to the persistent irritation.

Over time, this repeated injury and healing process can result in the formation of scar tissue, which narrows the esophagus. This narrowing, called an esophageal stricture, makes swallowing difficult. A more concerning complication is Barrett’s esophagus, where the normal cells lining the lower esophagus change into cells similar to those found in the intestine.

This cellular change is considered a precancerous condition, significantly raising the risk of developing esophageal adenocarcinoma, a type of cancer. Beyond the esophagus, the reflux of acid into the mouth can cause dental erosion, damaging tooth enamel. Aspiration of refluxed material into the airways can also aggravate or contribute to chronic lung issues, such as asthma and persistent bronchitis.

Diagnostic Procedures When Classic Symptoms Are Absent

Diagnosing GERD when a patient reports only atypical or silent symptoms requires specialized testing. The initial approach involves a thorough physical examination and a detailed patient history focused on extra-esophageal complaints. If reflux is suspected, a doctor may recommend an upper endoscopy, or esophagogastroduodenoscopy (EGD).

During an EGD, a flexible tube with a camera inspects the lining of the esophagus and stomach. This procedure checks for physical damage, such as esophagitis, strictures, or precancerous changes like Barrett’s esophagus. However, a normal endoscopy does not rule out GERD, as many patients with reflux have no visible damage.

The most definitive test for confirming silent or atypical reflux is ambulatory reflux monitoring, often using a 24-hour pH-impedance study. This test involves temporarily placing a thin catheter into the esophagus to measure both acidic and non-acidic reflux events over a full day. This comprehensive measurement is crucial because LPR symptoms can be caused by non-acidic reflux. In some cases, a doctor might recommend a trial of proton pump inhibitor (PPI) medication to see if symptoms improve, supporting a presumptive diagnosis.