Can You Have a Gallbladder Attack Without a Gallbladder?

A “gallbladder attack” refers to sudden, intense upper abdominal pain, often with nausea and vomiting, typically caused by gallstones blocking bile ducts. Even after gallbladder removal, similar severe pain can occur. This article explores why these symptoms arise and what they might signify.

The Gallbladder’s Role and Its Removal

The gallbladder is a small, pear-shaped organ located beneath the liver. Its primary function involves storing and concentrating bile, a digestive fluid produced by the liver. Bile is released into the small intestine to help break down fats during digestion.

Cholecystectomy, gallbladder removal surgery, is common for recurrent pain, inflammation (cholecystitis), or bile duct blockages caused by gallstones. The body adapts by having bile flow directly from the liver to the small intestine, though some individuals may still experience digestive issues.

Experiencing Pain After Gallbladder Surgery

Even after gallbladder removal, some individuals report symptoms similar to a gallbladder attack. These include upper right abdominal pain radiating to the back or shoulder, nausea, vomiting, indigestion, and bloating.

The medical term for persistent or new symptoms after cholecystectomy is Postcholecystectomy Syndrome (PCS). PCS can emerge immediately or years later, affecting an estimated 10% to 40% of patients.

Underlying Reasons for Post-Surgical Pain

Postcholecystectomy Syndrome (PCS) can stem from various causes, broadly categorized into biliary and non-biliary factors. Biliary causes are directly related to the bile ducts and account for approximately half of PCS cases.

A common biliary culprit is Sphincter of Oddi Dysfunction (SOD), where the muscular valve controlling bile and pancreatic fluid flow into the small intestine malfunctions. This leads to a backup of digestive juices, causing pain, nausea, and vomiting, often mirroring pre-surgery attacks.

Another reason for persistent pain can be retained or recurrent bile duct stones. These are gallstones that were either not completely removed during the initial surgery or new stones that form in the bile ducts thereafter, causing blockages. Bile leaks or strictures within the bile ducts, potentially resulting from surgical complications, can also contribute to discomfort. Furthermore, altered bile flow post-surgery can lead to bile salt-induced diarrhea, as bile continuously enters the intestine rather than being stored.

Non-biliary causes also account for about half of PCS cases and include conditions not directly related to the bile ducts. One such phenomenon is phantom pain, which is the sensation of pain in an organ that has been removed. Although more commonly associated with limb amputations, phantom pain can occur after the removal of internal organs, indicating a neurological origin. Additionally, other pre-existing gastrointestinal conditions like Irritable Bowel Syndrome (IBS), peptic ulcer disease, or even pancreatitis can become more apparent or exacerbated after gallbladder removal, producing symptoms that resemble gallbladder pain.

Identifying and Treating Persistent Symptoms

Diagnosing the cause of persistent post-surgical pain begins with a comprehensive medical history and physical examination. Healthcare providers often utilize imaging techniques such as ultrasound or CT scans to identify structural issues like retained stones or bile duct strictures. More specialized imaging, including Magnetic Resonance Cholangiopancreatography (MRCP) or Endoscopic Ultrasound (EUS), may be employed for a detailed view of the bile ducts and pancreas.

Endoscopic procedures like Endoscopic Retrograde Cholangiopancreatography (ERCP) allow direct visualization and intervention for issues such as bile duct stones or strictures. If Sphincter of Oddi Dysfunction (SOD) is suspected, Sphincter of Oddi Manometry (SOM) can measure the pressure within the sphincter to confirm its malfunction. Treatment approaches vary depending on the identified cause.

Medications, including pain relievers, antispasmodics for SOD, muscle relaxants, or bile acid sequestrants for diarrhea, may be prescribed. For structural problems, endoscopic interventions are common. Sphincterotomy, a procedure to cut the Sphincter of Oddi, can alleviate SOD, while ERCP can be used to remove retained stones. However, these interventions carry potential risks, such as pancreatitis.

Dietary and lifestyle modifications, like a low-fat diet or smaller, frequent meals, can help manage digestive adjustments. Always consult a healthcare professional for accurate diagnosis and a personalized treatment plan.