Can You Get a Sore Throat From Lack of Sleep?

Can a lack of sleep lead to a sore throat? Many people ponder this question when they wake with an uncomfortable feeling in their throat after insufficient rest. Sleep supports the body’s well-being and influences various physiological functions. Understanding the connection between sleep and bodily responses can show how sleep impacts our health, including throat comfort.

Sleep and Your Immune System

Sleep plays a central role in maintaining a healthy immune system. Adequate sleep allows the body to produce and release cytokines, proteins that coordinate the immune response and fight infection. It also helps generate protective antibodies and various infection-fighting cells, which are important for defense against pathogens.

Insufficient sleep reduces the production of these protective substances. Individuals sleeping less than seven hours per night are approximately three times more likely to develop a common cold than those getting eight hours or more. Even one night of reduced sleep can alter immune cell activity and increase inflammatory markers. This weakened immune response makes the body more susceptible to viral and bacterial infections, like the common cold or flu, which often cause a sore throat.

How Sleep Deprivation Physically Affects Your Throat

A lack of sleep can also physically irritate the throat. Tired individuals may sleep with their mouth open, causing throat tissues to dry out from increased mouth breathing.

Saliva production, which keeps the mouth and throat moist, naturally decreases at night. Combined with mouth breathing, this reduced saliva flow leads to dryness and a scratchy sensation upon waking. Dehydration, worsened by poor sleep or insufficient fluid intake, further contributes to throat dryness and irritation. Conditions like snoring or obstructive sleep apnea also promote mouth breathing, causing similar throat discomfort.

Beyond Sleep: Other Sore Throat Contributors

While a lack of sleep can contribute to throat discomfort, many other factors cause a sore throat. Frequent causes include viral infections like the common cold, influenza, mononucleosis, measles, chickenpox, or COVID-19. Bacterial infections, such as strep throat, also commonly cause throat pain.

Other contributors include allergic reactions to pollen, dust, or pet dander, often with irritating postnasal drip. Acid reflux, where stomach acid backs up into the esophagus, can cause a burning sensation. Environmental irritants like dry air, air pollution, or tobacco smoke also cause direct irritation. Overuse of the voice, such as from yelling or prolonged talking, can strain throat muscles and result in soreness.