Can You Get a Rash With the Flu? When to Be Concerned

A rash is not a typical symptom of influenza, but it can sometimes appear as a secondary manifestation. While the flu is primarily a respiratory illness, the body’s response to the viral infection or other co-occurring conditions can lead to skin changes. This article examines the nature of flu-related rashes and identifies situations where medical attention may be necessary.

Understanding Flu-Related Rashes

Studies suggest rashes occur in a small percentage of influenza A cases (around 2%) and have been observed in children with influenza B. These rashes are usually not directly caused by the influenza virus itself but are often a result of the body’s immune response to the infection, sometimes referred to as a viral exanthem.

A viral exanthem is a widespread rash accompanying a viral infection, characterized by spots, bumps, or blotches on the skin. This immune reaction leads to inflammation and visible skin changes. The appearance of such rashes can vary, including flat discolorations (macular), small raised spots (papular), or a combination (maculopapular). In rare, more severe cases, tiny pinpoint red or purple spots (petechial rash) might occur, particularly in children with H1N1 influenza.

Rashes associated with the flu can also stem from secondary infections. The flu virus can damage the nose and lung lining, creating an opportunity for bacterial complications. Common bacterial culprits include Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus, which can lead to conditions like pneumonia, sinusitis, or otitis. Medications used to alleviate flu symptoms, such as certain antibiotics or pain relievers, can also trigger allergic reactions that manifest as rashes.

When a Rash Appears: Distinguishing from Other Conditions

When a rash appears alongside flu-like symptoms, it is important to consider that other viral or bacterial infections might be the primary cause, rather than the flu itself. Many common childhood illnesses are well-known for causing distinct rashes and can present with symptoms similar to the flu. This overlap can make it challenging to pinpoint the exact cause without medical evaluation.

Measles typically presents with a rash that begins on the face and spreads downwards, often accompanied by systemic symptoms like fever, cough, and runny nose. Chickenpox is characterized by itchy, fluid-filled blisters that appear in successive crops across the body, along with fever and body aches. Hand-Foot-and-Mouth Disease (HFMD) often causes painful blisters in the mouth and on the palms and soles of the feet, usually affecting young children.

Fifth Disease, caused by parvovirus B19, is known for a distinctive bright red rash on the cheeks, sometimes called “slapped cheek” appearance, followed by a lacy rash on the body. Roseola, primarily affecting infants, usually starts with a high fever that subsides before a pink rash appears on the trunk. Scarlet fever, a bacterial infection often caused by Streptococcus pyogenes, results in a sandpaper-like rash and a sore throat. These conditions each have specific rash characteristics and accompanying symptoms that help differentiate them from a rare flu-related rash.

When to Seek Medical Attention

While many rashes that appear with flu-like symptoms are not serious and resolve on their own, certain signs indicate the need for prompt medical attention. A rapidly spreading rash, especially if it is painful, blistering, or purpuric (looks like bruises and does not blanch when pressed), warrants immediate evaluation. Blisters, peeling skin, or signs of infection such as pus, warmth, or swelling around the rash also require a doctor’s visit.

Accompanying symptoms that signal a more serious condition include difficulty breathing, severe headache, confusion, or neck stiffness. A high fever (over 102°F or 38.9°C) that does not respond to medication, seizures, or signs of dehydration are also red flags.

Individuals in high-risk groups, such as young children, adults over 65, pregnant women, or those with chronic medical conditions like asthma, diabetes, or heart disease, should seek medical advice promptly if a rash appears with flu symptoms. A healthcare provider can determine the underlying cause of the rash and ensure appropriate treatment.