Can You Get a False HPV Test Result?

While HPV tests are reliable screening tools, understanding the possibility of inaccurate results can help alleviate anxiety.

Understanding HPV Testing

Human papillomavirus (HPV) is a common virus, with certain types linked to an increased cancer risk. An HPV test detects high-risk HPV types in cervical cells, associated with cervical cancer. This differs from a Pap test, which identifies abnormal cell changes caused by HPV, rather than directly detecting the virus. The HPV test serves as a screening tool to identify individuals at risk for developing cervical pre-cancer and cancer, allowing for timely monitoring and intervention.

Types of Inaccurate HPV Results

HPV tests can sometimes yield results that do not perfectly reflect a person’s true HPV status. A false positive occurs when an HPV test indicates a high-risk HPV type is present, but the virus is not. This can lead to unnecessary anxiety and further follow-up, such as repeat testing or a cervical biopsy.

Conversely, a false negative means the HPV test indicates no high-risk HPV is present, even though the virus is in the body. This inaccurate result can delay detecting a persistent infection that might lead to cell changes. While rare for cervical cancer to be truly HPV-negative, false negatives can delay necessary monitoring or intervention. Regular screening remains important to mitigate these risks.

Reasons for Inaccurate HPV Results

Several factors can contribute to inaccurate HPV test results. Issues with sample collection, such as an insufficient or poorly collected cell sample, can lead to a false negative. Lab processing errors can also occur during sample analysis.

A low viral load (too little HPV present) can result in a false negative because the test may not detect the virus. Transient infections can also influence results; the body might clear the virus shortly after testing, or a very new infection might not yet be detectable. HPV tests have inherent sensitivity and specificity limitations, meaning a small margin for error exists. Some tests may also detect non-high-risk HPV types, contributing to false positives.

Navigating Inaccurate Results and Next Steps

Receiving an unexpected HPV test result can be concerning. Individuals should consult their healthcare provider to discuss the results and receive proper interpretation and guidance. A healthcare professional can explain what the specific results mean for an individual’s health.

Follow-up testing is often recommended to clarify or confirm HPV test results. This might include repeat HPV testing, a Pap test, or a colposcopy, which allows for a magnified view of the cervix and potential biopsy. Regular screening remains the most effective strategy for preventing cervical cancer, even with the possibility of inaccurate results.