Plasma donation collects the liquid portion of blood, plasma, for life-saving therapies and medications. Psoriasis is a common, chronic autoimmune skin condition characterized by patches of abnormal skin. Individuals often wonder if having psoriasis affects their ability to contribute to this resource. This article aims to clarify the eligibility requirements for plasma donation for those living with psoriasis.
General Plasma Donation Eligibility
To ensure donor and recipient safety, plasma donation centers have general eligibility requirements. Individuals typically need to be at least 18 years old and weigh a minimum of 110 pounds (approximately 50 kilograms). Donors must also pass a medical examination and complete a health history screening, including tests for transmissible viruses like hepatitis and HIV. Maintaining good overall health is a requirement, and donors are advised to follow a recommended diet and stay well-hydrated before donating.
Psoriasis and Plasma Donation Eligibility
Having psoriasis does not automatically disqualify an individual from donating plasma; many can donate if they meet other eligibility criteria. Eligibility depends on the specific characteristics of the condition, such as its severity, type, and current state of activity. For example, individuals with mild psoriasis that is well-controlled, especially with topical treatments, are often eligible to donate.
Donation centers assess each case individually during the screening process. However, certain situations related to psoriasis can lead to a temporary or permanent deferral. Active flare-ups, widespread skin lesions, or any signs of infection at the potential donation site may prevent donation. The presence of psoriatic arthritis, while not a disqualifier, can also influence eligibility if it involves active inflammation or requires specific medications.
Specific Factors Influencing Eligibility
Certain factors related to psoriasis can influence an individual’s eligibility to donate plasma, due to safety considerations for donors and recipients. Medications used to manage psoriasis are a consideration. Some systemic treatments, such as acitretin (Soriatane) and etretinate (Tegison), can lead to deferral periods.
For example, a waiting period of three years may be required after discontinuing acitretin, while etretinate can result in permanent ineligibility due to potential risks like birth defects if the plasma is transfused to a pregnant recipient. While many biologics and immunosuppressants used for psoriasis do not automatically disqualify a donor, the underlying condition they treat or their impact on the immune system can be a concern. Donation centers evaluate these medications carefully to ensure donor health and product safety, as immunosuppression may mask infections.
Active disease, such as widespread lesions or an ongoing flare-up, also leads to deferral, suggesting systemic inflammation or a potential risk of infection. If psoriasis affects the skin at the venipuncture site, or if there are open wounds or infections, donation may be deferred to prevent donor complications and plasma contamination.
Preparing for Plasma Donation with Psoriasis
For individuals with psoriasis considering plasma donation, preparation involves steps for a smooth and safe process. It is advisable to consult with your dermatologist or primary care physician beforehand to discuss your condition, current medications, and overall health status. This can help clarify any potential concerns before visiting a donation center. Medical professionals can offer guidance on whether donating plasma is suitable for your specific situation.
When you arrive at the donation center, it is essential to be transparent about your psoriasis, its severity, and all medications you are currently taking. Donation staff will conduct a medical screening and ask questions about your health history. Understanding that any deferral is implemented for safety reasons, protecting your well-being and plasma quality, can help manage expectations. General preparation steps like staying well-hydrated and eating a healthy, low-fat meal before your appointment are beneficial.