Can Vaping Cause Seizures? What the Science Says

Vaping has become a common practice, particularly among younger individuals. Many people wonder about the health implications associated with e-cigarette use. A significant concern revolves around whether vaping can lead to seizures.

Current Understanding of the Link

The U.S. Food and Drug Administration (FDA) has investigated a potential association between vaping and seizures. The FDA received 127 reports of seizures following e-cigarette use between 2010 and 2019, primarily affecting youth and young adults.

While these reports suggest a potential link, the FDA has emphasized that it is not yet definitively established that vaping directly causes seizures in all users. Investigations are ongoing to determine if a direct causal relationship exists and to identify common risk factors. The reports often lack specific details regarding the e-cigarette brand, the use of other substances, or any pre-existing medical conditions. Seizures were reported after varying durations of use, from just a few puffs to after a day or more of vaping.

Nicotine and Neurological Effects

Nicotine is a primary component in most e-liquids and affects the central nervous system. It interacts with nicotinic acetylcholine receptors (nAChRs) in the brain. This activation can increase neuro-excitability, which might contribute to the onset of seizures.

High concentrations of nicotine or rapid absorption can lower an individual’s seizure threshold. Nicotine poisoning, a result of excessive nicotine intake, is known to cause neurological symptoms, including seizures. E-liquids vary significantly in their nicotine content, which can influence the amount absorbed. Other components in e-liquids, such as propylene glycol and vegetable glycol, may also contribute to an increased risk of seizures.

Identifying Seizure Symptoms

Recognizing the signs of a seizure is important for immediate response. Seizure symptoms can vary widely. Common indicators include a brief period of confusion or a vacant staring spell.

Individuals may exhibit uncontrollable jerking movements of the arms and legs, or their body might stiffen suddenly. Loss of consciousness or awareness is also a frequent symptom. Other signs can involve changes in emotions or thinking, such as feelings of fear, anxiety, or a sense of déjà vu. Seizures typically last for a few seconds to several minutes.

Responding to a Seizure

Knowing how to respond during a seizure can help ensure the person’s safety. Remain calm and stay with the individual. Move any objects near the person that could cause injury. If the person is falling or on the ground, gently ease them into a side-lying position with their mouth pointing downwards to help keep their airway clear.

Place something soft and flat, like a folded jacket, under their head for protection. Loosen any tight clothing around their neck. Avoid restraining the person or placing anything in their mouth. Time the seizure; if it lasts longer than five minutes or if another seizure quickly follows, seek immediate medical attention by calling emergency services.

Factors Increasing Risk

Certain factors may increase an individual’s susceptibility to experiencing seizures potentially related to vaping. Those with pre-existing neurological conditions, such as a diagnosed seizure disorder or epilepsy, may be at higher risk. The co-use of other substances, including marijuana or amphetamines, has been noted in some reported cases and can also influence seizure risk.

Individuals using certain medications that might interact with nicotine or lower the seizure threshold could also face increased vulnerability. The high nicotine concentrations found in some e-liquids, combined with rapid nicotine delivery systems, present a notable risk, particularly for young people whose brains are still developing. Genetic predispositions or other underlying medical conditions can further contribute to an individual’s risk profile.