Can Vaping Cause a Collapsed Lung? What the Science Says

Vaping’s growing popularity has led to increased scrutiny regarding its health implications, particularly concerning the lungs. This article explores the scientific understanding of whether vaping can cause a collapsed lung, also known as pneumothorax. It details the mechanisms through which this might occur and outlines factors that could elevate an individual’s risk.

Understanding a Collapsed Lung

A collapsed lung, or pneumothorax, occurs when air leaks into the space between the lung and the chest wall (the pleural space). This trapped air exerts pressure on the lung, causing it to partially or completely deflate. The lungs are normally surrounded by two layers of membrane, the pleura, which allow smooth movement within the chest cavity.

Pneumothorax can arise from various causes, including injury, medical procedures, or spontaneously. Spontaneous pneumothorax often happens when small, air-filled sacs on the lung surface, called blebs or bullae, rupture and release air into the pleural space. Symptoms include sudden sharp chest pain (sometimes extending to the shoulder), shortness of breath, a rapid heart rate, and unusual fatigue.

The Vaping-Lung Collapse Connection

Vaping can contribute to a collapsed lung through mechanisms involving inflammation and tissue damage. E-cigarette aerosols contain chemicals that irritate and harm lung tissue. These include diacetyl, which damages small airways, and vitamin E acetate, found in illicit THC vaping products and linked to severe lung injuries.

Inhaling chemicals like acrolein and formaldehyde can lead to inflammation and degradation of lung cells. This chronic irritation weakens lung tissue, potentially forming fragile air sacs (blebs or bullae). If these weakened areas rupture, air leaks into the pleural space, causing a collapsed lung.

Additionally, the act of vaping itself can cause pressure changes within the lungs. Forceful inhalation or exhalation, similar to a Valsalva maneuver, significantly increases intrathoracic pressure. This increased pressure can cause weakened lung areas, such as pre-existing blebs, to rupture, facilitating a pneumothorax. Severe vaping-related lung injuries, known as E-cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI), also involve extensive lung damage that can predispose individuals to lung collapse.

Factors Increasing Risk of Vaping-Related Lung Collapse

Several factors can heighten the risk of a vaping-induced collapsed lung. Individuals with pre-existing lung conditions like asthma, COPD, or a history of spontaneous pneumothorax are more susceptible. Vaping can exacerbate these conditions, making the lungs more vulnerable.

Age and gender also play a role. Primary spontaneous pneumothorax is more frequently observed in tall, thin young men, typically between 10 and 30 years old. Vaping may compound this predisposition, potentially accelerating or triggering a lung collapse in those already at risk.

The type of vaping product and e-liquid used influences risk. High-nicotine e-liquids, certain flavorings (like diacetyl), and illicit or unregulated products containing vitamin E acetate or THC are associated with greater lung damage. These substances cause more severe inflammation and tissue injury, increasing the likelihood of bleb formation and rupture. The frequency and duration of vaping also contribute to cumulative exposure. Prolonged or heavy vaping leads to more extensive lung damage, elevating the long-term risk of a collapsed lung.

Concurrent use of other substances, especially traditional cigarettes or cannabis, significantly increases the danger. Dual use of e-cigarettes and combustible cigarettes substantially raises the risk of lung diseases and even lung cancer compared to using either product alone. Cannabis smoking is also linked to bullous lung disease and an elevated risk of pneumothorax, with vaping potentially exacerbating these effects.