Can Selenium Cause Constipation?

Selenium is an essential trace mineral. It plays a role in various bodily processes as a component of special proteins known as selenoproteins. These are obtained through dietary intake, as the body cannot produce selenium on its own.

Selenium’s Essential Functions

Selenium acts as an antioxidant, protecting cells from damage caused by free radicals, which are unstable molecules that can lead to oxidative stress. The mineral also plays a role in thyroid hormone metabolism, supporting the proper function of the thyroid gland, which has the highest concentration of selenium per unit weight of all tissues. Furthermore, selenium is important for immune system function, helping to regulate immune responses and the activity of white blood cells that fight infections.

Common Causes of Constipation

Constipation is a common digestive issue with many potential causes. A lack of dietary fiber, often found in fruits, vegetables, and whole grains, is a frequent contributor. Inadequate fluid intake, leading to dehydration, can also result in hard, dry stools that are difficult to pass. Other lifestyle factors such as insufficient physical activity, changes in routine like travel or diet, and ignoring the urge to have a bowel movement can lead to constipation. Certain medications, underlying medical conditions like thyroid disorders, and even stress or anxiety are also recognized causes.

Is There a Direct Link Between Selenium and Constipation?

At normal, recommended dietary or supplemental intake levels, selenium is generally not considered a direct or common cause of constipation. In fact, some research suggests an inverse relationship, where higher dietary selenium intake was associated with a lower likelihood of chronic constipation, particularly in men. Another study indicated that selenium supplementation improved functional constipation in children by increasing defecation frequency and normalizing stool consistency. Digestive upset from selenium, including gastrointestinal issues, is more commonly associated with excessive intake rather than normal consumption.

Selenium Toxicity: When Too Much Causes Digestive Issues

When selenium intake becomes excessive, it can lead to a condition called selenosis, or selenium toxicity. Symptoms often include gastrointestinal issues such as nausea, vomiting, and diarrhea. While diarrhea is a more frequently reported digestive symptom of selenium toxicity, abdominal discomfort and in some cases, constipation, can also occur. This happens because very high levels of selenium can irritate the gastrointestinal lining and interfere with normal metabolic processes. Other signs of selenosis include hair loss, brittle nails, fatigue, and a garlic-like odor on the breath.

Safe Selenium Levels and When to Seek Help

Safe Selenium Levels

To avoid selenium toxicity, adhere to recommended daily intake levels. For adults 19 years and older, the recommended dietary allowance (RDA) is 55 micrograms (mcg) per day. The tolerable upper intake level (UL), the maximum daily amount unlikely to cause adverse health effects, is 400 mcg per day. Individuals should be mindful of selenium content in their diet and any supplements, as Brazil nuts, for example, can contain a significant amount in a single serving.

When to Seek Help

If you suspect selenium is causing your constipation or if you are experiencing other symptoms of toxicity like persistent nausea, vomiting, hair loss, or brittle nails, consult a healthcare professional. These symptoms, especially if severe or accompanied by blood in the stool or unexplained weight loss, warrant medical attention. Self-diagnosing or self-treating with supplements without professional guidance is not recommended, as it can lead to further health complications.