Can Osteoporosis Cause Scoliosis?

The health of the skeletal system is deeply interconnected, meaning issues in one area of the spine can influence its overall alignment and strength. Many people are concerned about the relationship between two distinct conditions that compromise spinal integrity: osteoporosis, a disease affecting bone density, and scoliosis, defined by an abnormal spinal curve. While both disorders affect the vertebrae and are more prevalent with advancing age, their impact on the spine’s shape and structure is fundamentally different.

Defining Scoliosis and Osteoporosis

Scoliosis is defined as an abnormal, three-dimensional curvature of the spine that deviates laterally, or sideways, often resembling an “S” or “C” shape. This condition is usually accompanied by a rotational component of the vertebrae and is frequently diagnosed in adolescence (adolescent idiopathic scoliosis). The severity is measured using the Cobb angle; a measurement exceeding ten degrees is generally considered diagnostic.

Osteoporosis is a metabolic bone disease characterized by low bone mass and the deterioration of bone tissue microarchitecture. This leads to increased bone fragility and a significantly higher risk of fracture. The condition often progresses silently, with individuals sometimes unaware of the diagnosis until a bone break occurs, frequently in the hip, wrist, or spine. Osteoporosis is most commonly observed in older adults due to the progressive loss of bone mineral density.

Spinal Changes Caused by Bone Loss

The weakening of spinal bones due to osteoporosis directly results in structural changes, primarily through vertebral compression fractures (VCFs). These fractures occur when the weakened vertebral body cannot withstand normal pressure, sometimes even from routine activities like coughing or twisting. The front (anterior) portion of the vertebra collapses, causing the bone to take on a wedge shape.

The cumulative effect of multiple wedged vertebrae leads to an exaggerated forward curvature of the upper spine, known as hyperkyphosis. This pronounced forward hunch is commonly referred to as a “dowager’s hump” and is a hallmark of advanced osteoporosis. This deformity alters the spine’s contour in the sagittal plane (the view from the side), rather than the lateral plane (the view from the back). The change in alignment can also result in a measurable loss of height.

Is the Curvature True Scoliosis?

It is generally understood that osteoporosis does not cause classic idiopathic scoliosis, which is a primary structural issue often originating in youth. The spinal deformity resulting directly from osteoporosis is primarily kyphosis, the forward curvature caused by the uniform collapse of the front of the vertebrae. However, the relationship between bone loss and lateral curvature in older adults is complex.

Severe, asymmetric vertebral collapse due to osteoporosis can sometimes result in a secondary, non-idiopathic form of scoliosis. If compression fractures are uneven, collapsing more on one side of the vertebral body than the other, a lateral curvature can develop. This adult-onset curvature, often termed degenerative scoliosis, is frequently seen in combination with hyperkyphosis. It is distinct from the primary structural rotation found in idiopathic scoliosis.

Studies show that adults with osteoporosis are statistically more likely to develop a lateral spinal curve compared to those with healthy bone density, with some estimates suggesting the risk is six times higher. This secondary curvature is a consequence of the bone’s inability to maintain structural integrity under pressure, rather than a primary disease process of the spine. While the underlying cause is bone fragility, the resulting spinal deformity can include a component of lateral deviation that mimics scoliosis.