Can Naproxen Make You High? Explaining the Side Effects

Naproxen is a widely used medication available both over-the-counter and by prescription for managing pain and inflammation. Many individuals wonder if this common pain reliever can produce a euphoric or psychoactive “high.” Naproxen does not induce such effects, and understanding its action within the body clarifies why it does not alter consciousness. This medication is intended for therapeutic purposes, not for recreational use.

Understanding Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory drug (NSAID), a class of medications designed to reduce inflammation, pain, and fever. It functions by inhibiting specific enzymes, cyclooxygenase (COX-1 and COX-2), which are involved in the production of prostaglandins. Prostaglandins are natural substances in the body that contribute to inflammation, pain, and fever responses. By reducing prostaglandin synthesis, naproxen effectively alleviates these symptoms. This medication is not a controlled substance and does not act on the central nervous system in ways that induce euphoria or addiction.

Does Naproxen Produce a “High”?

Naproxen does not produce a euphoric or psychoactive “high” because its mechanism of action differs fundamentally from drugs that alter mood or consciousness. Unlike opioids, benzodiazepines, or stimulants, naproxen does not target brain receptors associated with reward, pleasure, or altered states of consciousness. Its purpose is to address physical discomfort by reducing inflammation and pain. Attempting to achieve a “high” by taking excessive amounts of naproxen is ineffective and carries substantial health risks.

Common Side Effects and Misinterpretations

While naproxen does not cause a “high,” it can lead to various side effects that some individuals might misinterpret. Common side effects include indigestion, heartburn, stomach pain, and nausea. Other frequently reported effects are headache, dizziness, and drowsiness. These sensations, such as feeling sleepy or lightheaded, are unintended reactions to the medication, not desirable psychoactive experiences. They are distinct from the euphoria or altered perception associated with recreational substances.

Recognizing an Overdose

Taking more than the recommended dose of naproxen can lead to an overdose, which is a serious medical emergency. Symptoms of a naproxen overdose can include severe drowsiness, stomach pain, nausea, and vomiting. In more severe cases, an overdose may result in confusion, blurred vision, and seizures. Overdosing can also lead to significant issues like kidney problems, including decreased urination, or gastrointestinal bleeding, which may manifest as black, tarry stools or vomiting blood. If an overdose is suspected, immediate medical attention is necessary. Contact a local emergency number or a poison control center.