Can Morton’s Neuroma Come Back After Treatment?

Morton’s neuroma is a condition affecting the forefoot, characterized by a thickening of the tissue surrounding one of the nerves leading to the toes. This typically occurs between the third and fourth toes. Irritation or compression of this nerve tissue causes burning pain, numbness, or the sensation of having a pebble lodged beneath the ball of the foot. A significant concern for patients is whether the pain will return after treatment. This possibility of recurrence is real, particularly following surgery, and understanding its mechanism is important for managing expectations.

Understanding Recurrence

Yes, Morton’s neuroma symptoms can return after treatment. Following surgery, the primary mechanism is the formation of a stump neuroma. This occurs when the nerve is severed during a neurectomy (the procedure to remove the damaged nerve segment). The body’s attempt to repair the cut nerve end leads to a disorganized growth of nerve fibers, resulting in a painful, bulb-shaped thickening at the site of the cut.

A stump neuroma is essentially a scar on the nerve ending, and it can become painfully irritated by scar tissue or pressure within the foot. Studies indicate that post-surgical pain, often due to a stump neuroma, can occur in up to 30% of patients following a neurectomy. This painful nodule typically forms in the weeks or months following the initial procedure. The likelihood of this complication is often related to the initial surgical technique, specifically if the nerve was not resected adequately or was not transposed deep into soft tissue to shield it from pressure.

Recurrence can also happen after non-surgical treatments, but the mechanism differs. If conservative measures like injections or orthotics reduce symptoms, the pain may return if the underlying biomechanical cause is not corrected. Continued use of narrow or high-heeled footwear, for example, can reignite the nerve compression and irritation. In these cases, the original neuroma may re-thicken or become symptomatic again due to ongoing mechanical stress.

Distinguishing Recurrence from Other Foot Pain

Not all forefoot pain after neuroma treatment signifies a true recurrence; other conditions can cause similar discomfort. Accurately diagnosing the source of persistent pain is important because treatment pathways differ significantly. True recurrent neuroma pain is often described as a sharp, shooting, or electrical sensation, frequently accompanied by numbness or tingling in the adjacent toes. This differs from mechanical pain, which is typically duller and more diffuse.

Conditions like metatarsalgia cause generalized pain across the ball of the foot due to inflammation of the metatarsal joints, without the specific nerve-related symptoms. Capsulitis, inflammation of the joint capsule, can mimic neuroma pain but is typically characterized by tenderness and pain when the toe joint is moved or extended. Stress fractures in the metatarsal bones or intermetatarsal bursitis (inflammation of the fluid-filled sacs between the toes) can also present as forefoot pain. A key distinguishing factor for a recurrent neuroma is the exquisite localized tenderness at the precise site of the nerve stump, which can be confirmed through a physical exam or diagnostic ultrasound.

Treatment Options for Recurrent Neuroma

Once a painful stump neuroma is definitively diagnosed, the treatment approach is often more complex than the initial therapy. Conservative options are usually attempted first, focusing on targeted nerve-specific interventions.

Non-Surgical Interventions

Ultrasound-guided alcohol sclerosing injections, administered directly to the stump, can chemically ablate the disorganized nerve tissue to reduce its size and pain signals. Cryotherapy, which involves using a specialized probe to freeze the nerve stump, is another minimally invasive technique that can be highly effective in desensitizing the area.

If non-surgical treatments fail to provide lasting relief, revision surgery may be necessary. This procedure is technically demanding and is often performed by surgeons specializing in nerve reconstruction. The goal of revision surgery is to excise the painful stump neuroma and transpose the remaining nerve end to a location free from pressure or friction. Surgeons may use a plantar (sole of the foot) approach to access the nerve more directly. The nerve stump is typically buried deep into muscle tissue or bone to prevent future irritation.

Prevention Strategies to Minimize Reoccurrence

Minimizing the risk of recurrence requires a long-term commitment to managing the biomechanical stresses that predispose the foot to nerve irritation. The most impactful preventive measure involves a permanent change in footwear habits. Individuals should consistently choose shoes with a wide toe box that allows the forefoot and toes to spread naturally, eliminating the compression that crowds the intermetatarsal nerves.

Avoiding high-heeled shoes is also strongly advised, as they shift body weight forward, significantly increasing pressure on the forefoot and the nerve endings. The use of custom-molded orthotics or metatarsal pads can help to redistribute pressure away from the affected nerve space. These devices work by lifting and separating the metatarsal bones, creating more space for the nerves. Regular activity modification, especially for high-impact activities that stress the forefoot, can also play a role in maintaining a pain-free status after successful treatment.