Can Measles Cause Infertility in Men and Women?

Measles is a highly contagious viral illness caused by the measles virus, spreading easily through airborne droplets when an infected person breathes, coughs, or sneezes. The virus can also survive on surfaces for up to two hours. A common concern is whether contracting measles can lead to infertility, and this article explores the potential links between measles infection and reproductive health in men and women.

How Measles Affects the Body

The measles virus initially replicates in the respiratory tract, then spreads throughout the body via the bloodstream, a process called viremia. This systemic spread allows the virus to infect various organs and tissues. It can damage the respiratory tract, leading to complications like bronchitis or pneumonia. The virus also impacts the immune system, potentially causing a temporary “immune amnesia” that leaves the body more vulnerable to secondary infections.

Measles and Male Reproductive Health

Measles can affect male reproductive health, primarily through orchitis, the inflammation of one or both testicles. While more commonly associated with mumps, orchitis can occur in post-pubertal males who contract measles, though it is rare. This inflammation typically appears 4-10 days after the onset of other measles symptoms.

When orchitis develops, the viral infection causes swelling within the testicles, disrupting normal sperm production. The inflammation can damage the seminiferous tubules and interstitial cells. This damage may lead to a reduced sperm count (oligozoospermia), absence of sperm (azoospermia), or impaired sperm quality.

Unilateral orchitis (affecting one testicle) usually does not result in sterility, though it can temporarily reduce sperm quality. However, bilateral orchitis (affecting both testicles) carries a higher risk of long-term fertility issues, with some studies indicating a 30-87% risk of infertility. In severe instances, prolonged inflammation can lead to testicular atrophy, a shrinking of the testicles, which can significantly reduce a man’s fertility potential.

Measles and Female Reproductive Health

The direct link between measles and female infertility is less established compared to male complications. While measles can, in very rare instances, cause oophoritis (inflammation of the ovaries), this complication is not frequently reported as a cause of long-term female infertility. Symptoms of oophoritis, if it occurs, are typically short-lived and resolve once the infection clears.

However, measles can indirectly impact female reproductive health, especially if contracted during pregnancy. Measles infection during pregnancy can increase the risk of adverse outcomes such as preterm birth, low birth weight, and potentially maternal death due to secondary infections like pneumonia. While measles has not been shown to cause congenital defects, severe maternal illness could lead to complications that indirectly affect fertility, though this is not a direct effect of the measles virus on reproductive organs. Overall, a direct impact of measles on female fertility is not commonly observed, and ongoing data collection continues to analyze potential connections.

Minimizing the Risk of Measles Complications

The most effective method to prevent measles and its associated complications is vaccination. The Measles, Mumps, and Rubella (MMR) vaccine is highly effective in preventing these diseases. Two doses of the MMR vaccine are typically recommended, providing protection against measles. One dose is about 93-95% effective, and two doses increase this effectiveness to 96-97%, offering long-term immunity.

For individuals who contract measles, treatment focuses on supportive care to manage symptoms and prevent complications. This includes maintaining hydration, managing fever, and addressing any secondary bacterial infections, such as pneumonia or ear infections, with appropriate antibiotics. Vitamin A supplementation may also be recommended, as it has been associated with reducing morbidity and mortality from measles. Prompt medical attention and supportive measures can help mitigate illness severity and reduce serious complications.