Can Lupus Make You Throw Up? Causes and What to Do

Systemic lupus erythematosus (SLE), commonly known as lupus, can lead to vomiting. While vomiting is not a universal symptom, it can occur as a direct manifestation of the disease affecting the gastrointestinal system or as a side effect of medications. Vomiting in lupus can have multiple origins, making diagnosis and treatment complex. Therefore, experiencing vomiting does not automatically indicate a lupus flare, as other factors can also contribute.

How Lupus Affects Digestion

Lupus can directly impact the digestive system through inflammation, a hallmark of this autoimmune disease. One specific manifestation is lupus enteritis, characterized by inflammation of the small intestine. This condition can lead to abdominal pain, nausea, and vomiting. Lupus enteritis is a serious complication where the disease targets the intestinal lining.

Another way lupus affects digestion is through vasculitis, inflammation of blood vessels. When vasculitis occurs in the blood vessels supplying the gut, it can impair blood flow to the intestines. This impaired circulation can cause severe abdominal pain, nausea, and vomiting, and lead to intestinal damage.

Lupus can also cause inflammation of the peritoneum, the lining of the abdominal cavity, known as peritonitis. This inflammation can lead to fluid accumulation in the abdomen, called ascites. This contributes to abdominal pain, tenderness, nausea, and vomiting.

Lupus can also lead to other digestive issues that cause vomiting, such as pancreatitis, inflammation of the pancreas. Symptoms of pancreatitis include abdominal pain that may spread to the back, along with nausea and vomiting. Additionally, some individuals with lupus may experience gastroesophageal reflux disease (GERD) due to inflammation in the esophagus or weakened esophageal muscles, where stomach acid flows back into the esophagus, causing heartburn and vomiting.

Medications and Other Causes of Vomiting

Medications prescribed for lupus can cause vomiting as a side effect. Non-steroidal anti-inflammatory drugs (NSAIDs) can irritate the stomach lining and lead to peptic ulcers, which may cause nausea and vomiting. Immunosuppressants and corticosteroids can similarly contribute to gastrointestinal upset, including vomiting.

Beyond medications, other common health issues unrelated to lupus activity can also cause vomiting. Viral or bacterial gastroenteritis, or stomach flu, can cause sudden onset of vomiting, diarrhea, and abdominal cramps. Migraines, which can co-occur, are frequently associated with nausea and vomiting. Other digestive disorders, such as irritable bowel syndrome (IBS) or food intolerances, can also trigger vomiting episodes.

When to Seek Medical Care

Prompt medical attention is important if vomiting is severe or persistent. Continuous vomiting can quickly lead to dehydration, indicated by decreased urination, excessive thirst, and a dry mouth. If vomiting is accompanied by severe abdominal pain, especially if sudden and intense, it warrants immediate evaluation.

Other warning signs include a fever alongside vomiting, which could indicate an infection or a serious lupus flare. The presence of blood in the vomit, which may appear red or like coffee grounds, is a serious symptom requiring immediate medical intervention. If vomiting significantly interferes with daily activities or prevents adequate fluid and food intake, consulting a healthcare provider is essential. A medical professional can diagnose the underlying cause and recommend the appropriate course of action.

Strategies for Managing Vomiting

Managing vomiting often involves specific dietary adjustments. Eating bland foods, such as plain rice, toast, or crackers, can help settle the stomach. Consuming small, frequent meals throughout the day rather than large ones can reduce the burden on the digestive system. Avoiding trigger foods, such as greasy, spicy, or highly acidic items, can alleviate symptoms.

Maintaining hydration is important when experiencing vomiting to prevent dehydration. Sipping clear liquids slowly, such as water, clear broths, or oral rehydration solutions, can replenish lost fluids and electrolytes. Avoid sugary drinks, caffeine, and alcohol, as these can worsen dehydration or stomach upset. Consulting with a doctor about anti-nausea medications can provide relief, but these should only be used under medical guidance.