Can Hypothyroidism Cause GERD? The Connection Explained

Hypothyroidism and Gastroesophageal Reflux Disease (GERD) are common health conditions. Many individuals wonder if a connection exists between them. This article explores the potential relationship between an underactive thyroid and chronic acid reflux, examining how one might influence the other.

Understanding Hypothyroidism

Hypothyroidism, or an underactive thyroid, occurs when the thyroid gland does not produce enough thyroid hormones. This gland, located at the front of the neck, regulates the body’s metabolism. Thyroid hormones influence nearly every organ and control energy use.

Low thyroid hormone levels can slow various bodily functions. Common symptoms include persistent fatigue, unexplained weight gain, increased sensitivity to cold, and constipation. Other signs are dry skin, thinning hair, muscle weakness, and depression. Diagnosis typically involves blood tests, measuring thyroid-stimulating hormone (TSH) and thyroxine (T4) levels.

Understanding GERD

Gastroesophageal Reflux Disease (GERD) is a chronic condition where stomach contents, including acid, persistently flow back into the esophagus. This acid reflux can irritate the esophageal lining. The lower esophageal sphincter (LES), a muscle at the junction of the esophagus and stomach, normally prevents this backflow by tightening after food passes.

Common symptoms of GERD include heartburn and regurgitation of sour liquid. Other symptoms are chest pain, difficulty swallowing, or a sensation of a lump in the throat. Factors contributing to GERD include obesity, certain dietary choices, and a hiatal hernia, where part of the stomach pushes through the diaphragm.

Exploring the Potential Connection

A link between hypothyroidism and GERD is suggested by several physiological mechanisms. Thyroid hormones regulate various digestive processes. When thyroid hormone levels are low, the entire digestive system can slow down, contributing to GERD symptoms.

One mechanism is reduced gastric motility, meaning the stomach empties more slowly. Low thyroid hormone levels can decrease the wave-like contractions (peristalsis) that move food through the digestive tract. This delay in stomach emptying can lead to prolonged acid exposure, increasing reflux likelihood.

Hypothyroidism may also affect the lower esophageal sphincter (LES) function. Research indicates low thyroid hormone levels can impact muscle function, potentially weakening the LES. A weakened LES may not close properly, allowing stomach acid to flow back into the esophagus more easily.

Impaired esophageal acid clearance can also occur. A healthy esophagus quickly clears refluxed acid back into the stomach through muscular contractions. However, in hypothyroidism, slower esophageal motility reduces the speed at which acid is cleared, prolonging irritation to the esophageal lining. The thyroid’s influence on the autonomic nervous system, which controls involuntary bodily functions including digestion, also suggests a broader impact on gastrointestinal health.

Recognizing Symptoms and Seeking Diagnosis

When GERD symptoms appear alongside other generalized symptoms, considering a potential thyroid connection is important. In individuals with undiagnosed or unmanaged hypothyroidism, GERD symptoms might present as persistent heartburn, regurgitation, or difficulty swallowing that does not respond well to typical treatments. Conversely, those with known hypothyroidism who develop new or worsening digestive issues might find their thyroid condition is contributing.

Seek a comprehensive medical evaluation from a healthcare professional for both conditions. A doctor can determine if GERD symptoms are atypical or severe enough for further investigation. Blood tests for thyroid function, specifically TSH and T4 levels, are effective ways to screen for hypothyroidism. Professional assessment, including medical history and physical examination, helps guide appropriate diagnostic steps.

Management Considerations

Effective management of hypothyroidism often involves thyroid hormone replacement therapy, typically with medication like levothyroxine. When low thyroid hormone levels are a contributing factor to GERD, optimizing thyroid function through proper treatment can significantly improve or even resolve associated GERD symptoms. This approach addresses the underlying systemic issue that might be impacting digestive health.

Alongside thyroid hormone replacement, general GERD management strategies remain important. These include making dietary adjustments, such as avoiding trigger foods like fatty or spicy items, chocolate, and caffeine. Lifestyle changes can also provide relief, such as eating smaller, more frequent meals, avoiding eating close to bedtime, and elevating the head of the bed during sleep. Maintaining a healthy weight and avoiding smoking are also beneficial for GERD management.