Can Ganglion Cysts Cause Nerve Damage?

A ganglion cyst is a non-cancerous, fluid-filled lump that often forms near joints or tendons. These cysts typically appear on the wrists, hands, ankles, or feet. They can range in size from as small as a pea to several centimeters across, and their size may fluctuate. While many ganglion cysts are harmless and may even disappear without intervention, their proximity to nerves can sometimes lead to complications. This article explores how ganglion cysts can interact with nearby nerves and the resulting implications.

How Ganglion Cysts Can Affect Nerves

Ganglion cysts can affect nerves primarily through compression. If a cyst grows close to a nerve, it can exert pressure on it, interfering with the nerve’s ability to transmit signals properly. This compression is more likely to occur with larger cysts or those located in confined anatomical spaces where there is limited room for expansion. The precise mechanism by which ganglion cysts form is not fully understood, but it is believed to involve a herniation or outpouching of the tissue surrounding a joint or tendon sheath. The fluid inside the cyst is thick and jelly-like, similar to synovial fluid, and when it accumulates, it can put mechanical pressure on adjacent nerves, leading to various neurological symptoms.

Recognizing Symptoms of Nerve Compression

When a ganglion cyst compresses a nerve, it can cause a range of symptoms. One common symptom is pain, which can be localized, radiating, sharp, or burning, intensifying with movement. Numbness or tingling sensations (paresthesia) are also frequently reported in the affected area. Individuals might experience weakness, muscle atrophy, difficulty with fine motor skills or grip strength, or changes in sensation like difficulty discerning hot or cold. Even small cysts can cause these symptoms if they are pressing on a nerve.

Diagnosis and Management

Diagnosing nerve involvement with a ganglion cyst typically begins with a physical examination. A healthcare provider will feel the lump, assess its characteristics, and evaluate sensation and strength in the affected area. Imaging tests, such as ultrasound or MRI, are often used to visualize the cyst’s size, exact location, and proximity to nerves. Nerve conduction studies or electromyography may also be performed to assess nerve function. These tests help determine the extent of nerve compression and guide treatment decisions.

Management varies depending on symptoms and nerve involvement; observation is recommended for asymptomatic cysts, as many resolve on their own. For symptomatic cysts, aspiration (draining fluid with a needle) can provide relief by reducing pressure, though recurrence is common (50-60%). Surgical excision, removing the entire cyst and its connection, is an option if other treatments are ineffective or if the cyst causes significant pain, functional impairment, or nerve compression. This surgery aims to relieve nerve pressure, has a lower recurrence rate (5-15%) compared to aspiration, and recovery can take several weeks, often requiring physical therapy.