Can Flaxseed Cause Miscarriage? What the Science Says

Flaxseed is a popular dietary addition due to its rich content of fiber and omega-3 fatty acids. It is often consumed ground or as an oil supplement for its benefits for heart health and digestion. For pregnant individuals, questions arise about the safety of incorporating this ingredient. The primary concern is whether compounds within flaxseed could increase the risk of adverse outcomes, such as miscarriage.

The Current Scientific Consensus on Safety

Current clinical data generally support the safety of consuming ground or whole flaxseed in typical dietary amounts during pregnancy. Direct evidence linking moderate flaxseed consumption to an increased risk of miscarriage in humans is lacking. Health authorities agree that the nutritional benefits of fiber and Alpha-linolenic acid (ALA) can be valuable when consumed appropriately.

A distinction must be made between consuming the seed and consuming concentrated flaxseed oil. Research identified a concern specifically with flaxseed oil supplementation, particularly in the second and third trimesters. One study indicated that the risk of premature birth was substantially higher in women who consumed the oil later in pregnancy. This suggests the potential risk is tied to the oil’s concentrated nature rather than the seed itself.

The scientific consensus is a qualified reassurance for moderate food-based consumption, typically defined as one to two tablespoons of ground flaxseed per day. Consuming the seed in these amounts does not carry the same risk profile as concentrated oil supplements.

The absence of a causal link in human studies is reassuring. However, research remains limited due to ethical constraints on conducting trials in pregnant populations. The focus remains on avoiding large, concentrated doses, which is a common recommendation for many supplements.

Components of Concern Phytoestrogens and Pregnancy

The anxiety surrounding flaxseed stems from its exceptionally high content of lignans, a class of compounds known as phytoestrogens. Flaxseed contains up to 800 times more lignans than most other plant foods. These lignans are metabolized into enterodiol and enterolactone, which are phytoestrogens with weak estrogen-like activity.

Phytoestrogens are plant-derived compounds structurally similar to the sex hormone estrogen. Because they interact with estrogen receptors, the theoretical concern is that high doses could disrupt the hormonal balance necessary for a healthy pregnancy. Estrogen and progesterone levels are precisely regulated throughout gestation, and interference could pose a risk.

Animal studies, primarily in rats, have investigated the effects of high-dose flaxseed consumption, often using concentrations far exceeding typical human dietary intake. These studies suggest that exposure to high amounts of lignans during pregnancy could affect the reproductive development of the offspring. This evidence underscores the need for caution with concentrated forms.

The estrogenic activity of these plant compounds is much weaker than the body’s own endogenous estrogen. The amount of lignans obtained from moderate dietary intake is significantly lower than the doses used in high-exposure animal experiments. This contrast helps explain why the theoretical risk observed in a laboratory setting does not translate to harm from moderate consumption.

Practical Guidelines for Consumption During Pregnancy

For pregnant individuals, the form of flaxseed consumed is an important consideration. Ground flaxseed is the preferred option because the nutrients are significantly more bioavailable than in whole flaxseed. Whole seeds often pass through the digestive tract undigested, meaning the body does not absorb the beneficial Alpha-linolenic acid (ALA) and lignans.

The recommended daily limit for ground flaxseed is a conservative one to two tablespoons. This amount provides a substantial dose of omega-3 fatty acids and fiber without delivering high concentrations of lignans. This moderate intake helps manage common pregnancy issues like constipation while contributing healthy fats.

Flaxseed oil should be approached with greater caution, especially during the later stages of pregnancy. Although the oil is a concentrated source of ALA, it lacks the fiber and lignans found in the seed. This is the form specifically associated with an increased risk of premature birth. It is advisable to avoid flaxseed oil supplements during pregnancy.

Pregnant individuals should avoid large, medicinal doses of flaxseed or concentrated lignan supplements. Before making any significant changes to the diet or starting any new supplement, consulting with a healthcare provider or a registered dietitian is the most prudent step.