Can Diverticular Disease Cause Cancer?

Diverticular disease often leads to questions about its potential association with more serious conditions like colorectal cancer. Understanding the relationship between these two health concerns is important. This article explores the current medical understanding of diverticular disease and colorectal cancer, examining if one can lead to the other and highlighting shared risk factors and preventive strategies.

Understanding Diverticular Disease

Diverticular disease involves small, bulging pouches, known as diverticula, forming in the lining of the large intestine (colon). These pouches typically develop in weak spots of the colon wall and are common, especially in individuals over 50. The presence of these pouches without symptoms is termed diverticulosis.

If these pouches become inflamed or infected, the condition is called diverticulitis. Symptoms often include abdominal pain, commonly felt in the lower left side of the abdomen, fever, nausea, vomiting, chills, or changes in bowel habits such as constipation or diarrhea.

Understanding Colorectal Cancer

Colorectal cancer originates in the colon or rectum. It typically begins as small, non-cancerous growths called polyps on the inner lining of the colon. Over time, some polyps can develop into cancer.

Colorectal cancer is a significant global health concern and a leading cause of cancer-related deaths. Risk factors include increasing age, a personal or family history of colorectal cancer or polyps, and inflammatory bowel diseases. Lifestyle elements such as a low-fiber, high-fat diet, lack of regular physical activity, obesity, smoking, and heavy alcohol consumption also contribute to the risk.

The Link Between Diverticular Disease and Colorectal Cancer

Medical evidence suggests that diverticular disease does not directly cause colorectal cancer. The perceived connection often arises from their shared common risk factors. Both conditions are more prevalent with increasing age and are associated with lifestyle factors.

Shared risk factors include a diet low in fiber, high consumption of red and processed meats, physical inactivity, obesity, and smoking. These factors can predispose individuals to develop both diverticular disease and colorectal cancer independently. Chronic inflammation, which can occur in diverticulitis, might also play a role in the broader association between diverticular disease and certain cancers.

Symptoms of diverticular disease can sometimes overlap with or mask those of colorectal cancer, presenting diagnostic challenges. Abdominal pain, changes in bowel habits, and rectal bleeding can be present in both conditions. This overlap means an individual experiencing symptoms of diverticular disease might also have an undetected colorectal cancer, leading to an increased diagnosis rate shortly after a diverticulitis diagnosis. Studies have shown a slightly increased risk of colorectal cancer diagnosis within the first 6 to 12 months following a diverticulitis episode, which is primarily attributed to increased medical surveillance and screening during that period. Therefore, medical professionals often recommend a colonoscopy after an episode of diverticulitis to rule out colorectal cancer.

Recognizing Symptoms and Seeking Medical Advice

Awareness of symptoms is important for both diverticular disease and potential colorectal cancer. Persistent or concerning changes warrant medical evaluation. For diverticular disease, symptoms such as chronic abdominal pain, particularly in the lower left side, bloating, or changes in bowel habits like constipation or diarrhea, should be monitored.

For potential colorectal cancer, key symptoms include a persistent change in bowel habits, such as new or worsening diarrhea or constipation, or a change in stool consistency. Rectal bleeding or blood in the stool, unexplained weight loss, persistent abdominal discomfort (cramps, gas, or pain), and ongoing fatigue are also signs to discuss with a healthcare provider. Seeking medical advice promptly for any of these lasting symptoms allows for proper diagnosis and timely management.

Preventive Measures and Screening

Adopting certain lifestyle practices can help reduce the risk of both diverticular disease complications and colorectal cancer. A diet rich in fiber, including fruits, vegetables, and whole grains, promotes healthy bowel function and may help prevent the formation of diverticula and reduce the risk of colorectal cancer. Limiting the intake of red and processed meats is also advised.

Maintaining a healthy body weight and engaging in regular physical activity are beneficial for overall gut health and can lower the risk for both conditions. Limiting alcohol consumption and avoiding smoking further contribute to reducing cancer risk. Beyond lifestyle, age-appropriate colorectal cancer screenings are important for early detection. For individuals at average risk, screening typically begins around age 45 or 50, often involving colonoscopies every 10 years or stool-based tests at regular intervals.