Can Chemo Cause Stomach Pain & What to Do About It?

Chemotherapy, a common cancer treatment, can cause stomach pain. Chemotherapy medications target rapidly dividing cells, including cancerous cells. However, healthy cells that also divide quickly, such as those lining the digestive tract, are also affected. This non-specific targeting leads to various gastrointestinal side effects, including stomach discomfort.

How Chemotherapy Impacts the Digestive System

Chemotherapy drugs affect the gastrointestinal (GI) tract by damaging its rapidly dividing cells. This damage can lead to mucositis, an inflammation of the mucous membranes lining the entire digestive system, from the mouth to the intestines. Mucositis can result in symptoms like abdominal pain, nausea, vomiting, and diarrhea. This inflammation impairs the gut’s absorptive and barrier functions, contributing to discomfort.

Chemotherapy can also alter gut motility, the wave-like action that moves food through the intestines. Some chemotherapy drugs can either speed up or slow down this process. Rapid motility may lead to diarrhea and cramping, while slowed motility can cause constipation, hard stools, and associated pain. Additionally, chemotherapy can disrupt the balance of the gut microbiota, the community of bacteria residing in the intestines. This imbalance, known as dysbiosis, can further contribute to digestive problems, including abdominal pain, bloating, and gas.

Recognizing Chemotherapy-Related Stomach Discomfort

Stomach discomfort from chemotherapy can manifest in diverse ways, ranging in intensity and type. Individuals might experience cramping, described as a painful, tight feeling in the belly muscles that can come in waves. Bloating is another common symptom, where the abdomen may appear enlarged or feel as if a balloon has inflated inside. This can be accompanied by increased gas and a general sense of fullness.

Nausea and indigestion are frequently reported, which can contribute to overall abdominal distress. The pain can be a dull, persistent ache or a sharp, intense sensation. While some individuals may experience mild discomfort, others might face severe pain that significantly affects their daily life.

Strategies for Managing Stomach Pain During Chemotherapy

Managing stomach pain during chemotherapy often involves dietary adjustments and medical interventions. Eating small, frequent meals throughout the day can be beneficial, as it reduces the load on the digestive system. Opting for bland foods and avoiding those known to trigger discomfort, such as spicy, greasy, or high-fiber foods, can help minimize irritation. Some individuals may also find it helpful to limit dairy products, as chemotherapy can temporarily affect lactose digestion.

Maintaining adequate hydration is important, so sipping clear liquids like water, flat soda, or pulpless fruit juice between meals can be useful. Healthcare providers may recommend over-the-counter remedies, such as antacids for indigestion or anti-diarrheals for loose stools. Anti-nausea medications are frequently prescribed to manage chemotherapy-induced nausea and vomiting, which can indirectly alleviate stomach discomfort. Always discuss any new remedies or dietary changes with your healthcare team before implementing them to ensure they are appropriate for your specific treatment plan.

When to Contact Your Healthcare Team

While some stomach discomfort is expected during chemotherapy, certain symptoms warrant immediate communication with your healthcare team. Seek medical attention for severe, worsening, or unbearable stomach pain that does not improve with prescribed medications or self-care strategies. The presence of a fever (100.5 degrees Fahrenheit or higher) or chills alongside stomach pain could indicate an infection, requiring prompt evaluation.

Persistent vomiting or diarrhea, especially if it lasts more than two days, is a serious concern as it can lead to dehydration and electrolyte imbalances. Any signs of blood in stool or vomit also necessitate urgent medical assessment. Inform your healthcare team of any significant changes in your symptoms or overall condition, as early intervention can prevent complications.