Can Carvedilol Cause Hair Loss?

Carvedilol is a beta-blocker prescribed to manage high blood pressure, heart failure, and to improve survival after a heart attack. Like all medications, Carvedilol can cause side effects, and some patients express concern about potential hair loss. Although the drug is highly effective for cardiovascular uses, its potential to affect hair growth is a topic worth exploring.

Carvedilol and Hair Loss Incidence

The relationship between Carvedilol and hair loss, known as alopecia, is uncommon. Official prescribing information lists hair loss as a possible adverse reaction, but it is categorized as a rare side effect. Clinical studies typically report the incidence of alopecia as less than 1% of patients, placing it among the least frequently observed side effects. The vast majority of individuals using Carvedilol do not experience noticeable hair thinning. Carvedilol’s link to hair loss is considered less frequent than that of other beta-blockers.

How Medication Affects the Hair Growth Cycle

Medication-induced hair loss is usually linked to Telogen Effluvium (TE), a temporary condition. TE occurs when a systemic stressor, such as a drug or illness, disrupts the normal hair growth cycle, which includes the Anagen (growth), Catagen (transition), and Telogen (resting/shedding) phases. Medications can prematurely force a large number of growing hair follicles into the resting phase. Noticeable hair loss typically begins two to four months after starting the medication, as the mass conversion into the Telogen phase does not cause immediate shedding. The mechanism by which beta-blockers like Carvedilol cause this shift is not fully understood, but it may relate to changes in signaling pathways that regulate the hair follicle. TE results in diffuse thinning across the entire scalp and is generally reversible once the medication is adjusted or removed.

Consulting Your Doctor and Next Steps

If increased hair shedding occurs after starting Carvedilol, consult the prescribing physician immediately. A doctor must confirm the link and rule out other common causes of hair loss, such as stress, thyroid issues, or vitamin deficiencies. Sudden, unsupervised discontinuation of Carvedilol can be dangerous, potentially causing rebound hypertension (a sharp rise in blood pressure) or worsening heart failure symptoms. Your physician will evaluate your health and may consider adjusting the dosage or switching to an alternative medication if Carvedilol is confirmed as the cause. Once the trigger is managed, hair regrowth typically begins within a few months.