Can Breast Reduction Surgery Cause Cancer?

Reduction mammoplasty, commonly known as breast reduction surgery, alleviates physical discomfort and improves the quality of life for individuals with excessively large breasts. The procedure involves removing a portion of the breast tissue, skin, and fat to create a smaller, lighter breast contour. Medical research consistently shows that having a breast reduction does not cause or increase a person’s risk of developing breast cancer in the future.

Does Breast Reduction Influence Cancer Risk

The idea that breast reduction could increase cancer risk is a misconception not supported by scientific evidence. Studies suggest the procedure may be associated with a reduced incidence of breast cancer compared to the general population. This effect is attributed to the surgery physically removing a significant amount of the glandular tissue where most breast cancers originate.

Breast cancer risk is directly proportional to the amount of glandular tissue present. Removing this tissue decreases the total volume of cells that could undergo malignant change. Research indicates that the degree of risk reduction may correlate with the amount of tissue removed during the procedure.

While the surgery is performed for symptoms related to macromastia, not for cancer prevention, its effect on tissue volume is a beneficial side effect. A large-scale analysis in Denmark found that breast cancer risk was significantly lower in women who had undergone reduction mammoplasty, particularly those over the age of 40. This finding supports the theory that removing tissue reduces the cellular pool at risk.

The dominant factors influencing a person’s lifetime cancer risk, such as genetics, hormonal exposure, and lifestyle, remain the same regardless of the surgery. The procedure does not eliminate risk entirely, as some glandular tissue must remain to preserve the breast shape and structure. However, the physical reduction of at-risk tissue contributes to a generally favorable or neutral risk profile post-operation.

Impact on Future Cancer Detection

Breast reduction permanently alters the internal architecture of the breast, which has implications for future screening. The removal and rearrangement of tissue lead to internal scarring and changes in density patterns seen on imaging. This altered structure necessitates careful consideration when interpreting diagnostic tests like mammograms.

After the initial healing period, typically around six months, a new baseline mammogram is recommended to document the post-surgical appearance. This new image becomes the standard for comparison against all future screenings. Radiologists must be informed of the surgical history, as scar tissue can sometimes mimic the appearance of suspicious lesions on a mammogram.

The reduced breast volume can make the remaining tissue easier to compress during a mammogram, potentially improving comfort during the procedure. With less overall dense tissue to obscure abnormalities, the accuracy of mammography and supplementary imaging like ultrasound can sometimes be enhanced. Detection remains highly effective, though the screening method may be adapted to account for the surgical changes.

Unexpected Cancer Diagnoses During Surgery

A standard protocol during reduction mammoplasty is sending all removed breast tissue to a pathologist for microscopic examination. This practice ensures the tissue is healthy and checks for any pre-existing, undiagnosed conditions. In a small fraction of cases, this examination reveals a cancer or a high-risk precancerous lesion that was previously occult.

The incidence of finding a frank malignancy, such as invasive carcinoma or ductal carcinoma in situ, is low, often less than 1% of all reduction mammoplasty specimens. High-risk lesions like atypical hyperplasia are slightly more common. The discovery of such an incidental finding means the patient already had the condition, and the surgery effectively led to its early detection and removal.

When a malignancy or high-risk lesion is found, the pathology report is immediately shared with the patient and their surgical team. This prompts a referral to a breast cancer specialist or surgical oncologist for a comprehensive follow-up consultation. Subsequent steps may include further imaging, increased surveillance, or additional treatment, depending on the type and extent of the cells found.