Can Arthritis in the Knee Cause Pain in the Leg?

Arthritis, particularly osteoarthritis, is the progressive wear and tear of the cartilage that cushions the knee joint, leading to inflammation and pain at the joint line. While the origin of the problem lies within the knee, the resulting pain can certainly radiate or manifest throughout the rest of the limb. This secondary leg pain is a complex response, resulting from both mechanical changes in the way a person moves and neurological signals.

How Gait Changes Cause Leg Pain

When the knee joint is painful, the body naturally attempts to protect it by altering the way a person walks, known as biomechanical compensation. This protective change in gait is an unconscious effort to shift weight away from the damaged area, immediately changing the forces applied to the entire leg. Individuals often adopt a shorter, slower stride or may slightly limp to reduce pressure on the painful knee.

This altered movement pattern forces other muscles and joints to work harder or in an unnatural way to maintain stability and motion. Muscles in the hip, thigh, and calf are recruited differently to compensate for the knee’s limited range of motion and weight-bearing capacity. This abnormal strain leads to muscular fatigue and pain in the hip flexors, gluteal muscles, or calf muscles, which is then felt as leg pain. This discomfort is typically mechanical, stemming from muscle and tendon overuse rather than directly from the arthritic joint itself.

Nerve Compression and Referred Pain Pathways

Another cause of leg pain related to knee arthritis involves the nervous system, resulting in referred pain. Referred pain occurs when the brain interprets pain signals originating in one location as coming from a completely different area, often further down the limb. Inflammation and physical changes associated with advanced knee arthritis, such as swelling or bone spurs, can irritate or compress nearby sensory nerves.

Nerve branches passing near the knee, like the saphenous nerve, can become affected by the surrounding joint pathology. When these nerves are irritated, they transmit pain signals felt as burning, tingling, or shooting discomfort that travels down the leg, sometimes reaching the shin or calf. This discomfort resembles symptoms associated with mild sciatica, although the root cause is local irritation at the knee joint, not a lower back problem.

When Leg Pain Requires Medical Evaluation

While most leg pain associated with knee arthritis is related to mechanical strain or referred nerve signals, certain symptoms warrant immediate medical attention because they may indicate a serious, unrelated condition. It is important to watch for specific “red flags” that are not typical of stable, chronic arthritis pain.

These red flags include:

  • Sudden, severe, and unexplained pain, especially when accompanied by significant swelling localized to one calf or leg.
  • One-sided warmth, redness, or skin discoloration in the leg, particularly with a throbbing ache that does not improve with rest, which could be a sign of deep vein thrombosis (DVT).
  • Leg pain accompanied by a fever, a sudden inability to bear weight, or a rapid loss of sensation or weakness.

For chronic, persistent leg pain suspected to be related to arthritis, consulting a rheumatologist or orthopedic specialist can help differentiate the cause. They can establish an appropriate management plan based on the source of the discomfort.