Can Arthritis Cause Neuropathy and Nerve Damage?

Arthritis, primarily known for its impact on joints, can also be linked to nerve damage, known as neuropathy. This article explores how certain forms of arthritis can lead to neuropathy, exploring mechanisms, recognition, and management of associated symptoms.

What is Arthritis?

Arthritis refers to a group of over 100 diseases characterized by joint inflammation. This inflammation typically causes pain, stiffness, and sometimes swelling, limiting movement.

The two most common types are osteoarthritis (OA) and rheumatoid arthritis (RA). Osteoarthritis often results from the breakdown of cartilage, the protective tissue cushioning bones, leading to bones rubbing together. Rheumatoid arthritis, an autoimmune disease, occurs when the body’s immune system mistakenly attacks its own healthy joint tissues, leading to widespread inflammation and potential joint damage.

What is Neuropathy?

Neuropathy involves damage or disease affecting peripheral nerves. These nerves transmit signals between the brain and spinal cord and the rest of the body, including hands, feet, muscles, and internal organs. Damage can impair sensation, movement, and organ function.

Symptoms commonly include weakness, numbness, tingling, or pain, often starting in the hands and feet. Neuropathy can affect sensory, motor, or autonomic nerve fibers. It can affect a single nerve (mononeuropathy) or multiple nerves (polyneuropathy).

How Arthritis Can Lead to Neuropathy

Arthritis can lead to neuropathy through several mechanisms. Inflammation and structural changes associated with arthritis can directly or indirectly affect nerve health, leading to nerve compression, systemic inflammation, blood vessel issues, or medication side effects.

Nerve compression is a common mechanism. Swelling, inflammation, or bone changes around arthritic joints can put pressure on nearby nerves. For example, in rheumatoid arthritis, inflamed joint linings or tendons can compress nerves, causing carpal tunnel syndrome. Osteoarthritis in the spine can cause bone spurs that pinch nerves, causing pain or numbness in the arms or legs.

Systemic inflammation, particularly in autoimmune forms of arthritis like rheumatoid arthritis, can also damage nerves. Chronic, widespread inflammation can directly harm nerve fibers or the small blood vessels that supply them with nutrients. This inflammatory environment can disrupt nerve function, leading to various neurological symptoms.

Vasculitis, an inflammation of blood vessels, represents another mechanism. In some severe cases of autoimmune arthritis, the immune system may attack blood vessels, including those supplying the nerves. This reduces blood flow to the nerves, leading to oxygen and nutrient deprivation, resulting in nerve damage. This type of neuropathy is often observed in people with long-standing rheumatoid arthritis.

Some arthritis medications may contribute to neuropathy as a side effect. Other health conditions often seen alongside arthritis, such as diabetes, can also independently contribute to neuropathy, complicating the clinical picture.

Recognizing Neuropathy Symptoms with Arthritis

Recognizing neuropathy symptoms with arthritis can be challenging due to symptom overlap with joint pain. Neuropathy often presents with distinct sensations. Common symptoms include tingling, a “pins and needles” sensation, burning, or shooting pain. These sensations frequently begin in the hands or feet and can gradually spread upwards into the limbs.

People might also experience numbness, reduced ability to feel touch or temperature, or muscle weakness. Loss of balance can occur, particularly if motor or sensory nerves are affected. Consulting a healthcare professional is important for diagnosis, as these symptoms can indicate nerve damage.

Approaches to Managing Neuropathy in Arthritis

Managing neuropathy when it co-occurs with arthritis involves a comprehensive strategy focused on both conditions. A primary approach involves controlling the underlying arthritis activity, especially in inflammatory types. Effective management of joint inflammation can help alleviate nerve compression and reduce systemic damage to nerves. This includes therapies to calm the immune response contributing to arthritis progression.

Symptomatic relief for nerve pain is another important component. Certain medications, such as those that adjust nerve signals, can help reduce discomfort. Physical therapy is often recommended to improve strength, flexibility, and balance, which can be affected by nerve damage. Learning new ways to perform daily tasks can also help protect affected nerves and improve function.

Lifestyle modifications also play a role in supporting nerve health. Regular, gentle exercise and a balanced diet can contribute to overall well-being and potentially reduce inflammation. Avoiding activities that aggravate nerve symptoms is advisable. A multidisciplinary care team, including rheumatologists, neurologists, and physical therapists, can provide integrated care, addressing both conditions for improved outcomes.