Can an Ovarian Cyst Cause a Missed Period?

Experiencing a missed or delayed period often leads to concerns about reproductive health, including the possibility of an ovarian cyst. An ovarian cyst is a common, fluid-filled sac that develops on or inside an ovary. While most are harmless and temporary, they can occasionally interfere with the hormonal balance governing the menstrual cycle. This article explores the specific ways certain ovarian cysts can disrupt the monthly rhythm and examines the more common reasons a period might be late.

Understanding the Menstrual Cycle and Ovarian Cysts

The menstrual cycle is a complex process driven by the rhythmic rise and fall of hormones, primarily estrogen and progesterone. The cycle begins when the pituitary gland releases follicle-stimulating hormone (FSH), prompting a follicle in the ovary to mature an egg. Once the egg is released during ovulation, the remaining follicle transforms into a structure called the corpus luteum, which produces progesterone to prepare the uterine lining for a potential pregnancy. If pregnancy does not occur, the corpus luteum breaks down, progesterone levels drop, and the uterine lining is shed as a period.

Ovarian cysts are broadly categorized into two main types: functional and pathological. Functional cysts are the most common and are directly related to the menstrual cycle. They include follicular and corpus luteum cysts, forming when a normal part of the cycle does not complete its process. Pathological cysts, such as dermoid cysts or endometriomas, are not related to the monthly cycle and form due to abnormal cell growth or underlying conditions.

The Direct Link Cysts and Cycle Disruption

The majority of ovarian cysts, including small, simple functional cysts, typically do not cause a period to be missed or delayed. These cysts usually resolve on their own within a few weeks, allowing the hormonal cycle to continue. However, certain functional cysts can directly interfere with the hormonal signals that trigger menstruation.

A follicular cyst forms if the follicle fails to rupture and release the egg during ovulation. Since the egg is not released, the corpus luteum does not form, meaning progesterone production is delayed or absent. This prolonged phase of low progesterone prevents the uterine lining from shedding on time, resulting in a delayed or missed period.

Similarly, a corpus luteum cyst develops if the sac that forms after ovulation reseals and fills with fluid, continuing to produce progesterone beyond its normal lifespan. This extended progesterone production maintains the uterine lining, delaying the expected drop in hormones that triggers menstruation. The period begins only once the cyst shrinks and the progesterone level falls.

When multiple cysts are present, the cause is often an underlying condition like Polycystic Ovary Syndrome (PCOS). PCOS involves a hormonal imbalance where elevated levels of androgens, often driven by insulin resistance, prevent the ovaries from regularly releasing an egg. The small follicles that cannot mature and ovulate accumulate on the ovaries, appearing as multiple small cysts on an ultrasound. The resulting chronic lack of ovulation is the primary reason for the missed or highly irregular periods experienced by many with PCOS.

Other Common Reasons for a Late or Missed Period

While ovarian cysts can be a factor, most delayed periods are caused by other physiological or lifestyle factors. The most frequent reason for a missed period in a sexually active person is pregnancy, which should always be ruled out first with a home test. Beyond pregnancy, the reproductive system is highly sensitive to external and internal stressors.

Significant psychological or physical stress elevates levels of the hormone cortisol, disrupting the communication pathway between the brain and the ovaries (the hypothalamic-pituitary-ovarian axis). This disruption can temporarily halt ovulation, leading to a missed period, medically known as hypothalamic amenorrhea.

Changes in body weight heavily influence hormonal balance. Both low body weight and high body fat percentage can interfere with reproductive hormone production. Sudden weight loss or gain, or overly intense exercise without adequate calorie intake, can signal that conditions are unfavorable for reproduction, causing ovulation to stop.

Certain medications can also affect the timing of the menstrual cycle. Hormonal birth control, particularly progestin-only methods, can cause periods to become light, irregular, or absent. Non-hormonal medications, including some antidepressants, antipsychotics, and thyroid medications, can also impact the hormonal balance. Finally, the natural transition into perimenopause can cause periods to become shorter, longer, lighter, or missed entirely as ovarian function slows.

Next Steps and When to Consult a Healthcare Provider

If a period is late, the first step is to take a home pregnancy test, as this is the most common cause. If the test is negative, tracking symptoms and waiting is often sufficient, especially if stress or significant lifestyle changes have occurred. However, a delayed period should prompt a visit to a healthcare provider in certain situations.

It is recommended to schedule an appointment if a period is missed three consecutive times, or if the delay is accompanied by severe, sudden pelvic pain, which could indicate a cyst rupture or ovarian torsion. A consultation is also necessary if a missed period occurs alongside other unusual symptoms, such as unexplained weight gain, excessive facial or body hair growth, or persistent pelvic discomfort.

A healthcare provider will typically begin the diagnostic process with a physical exam and blood work to check hormone levels and rule out other conditions like thyroid issues. If a cyst is suspected, a pelvic ultrasound can be performed to visualize the ovaries, determine the cyst’s size and composition, and guide management. Management options range from watchful waiting for simple cysts to hormonal therapy or, rarely, surgical removal.