Can Allergy Testing Make You Sick?

Allergy testing involves exposing individuals to small amounts of potential allergens in a controlled setting. This process helps healthcare providers identify specific substances that trigger an immune system overreaction. By pinpointing these triggers, testing provides valuable information for managing symptoms and developing a suitable treatment plan.

Expected Reactions from Common Allergy Tests

Common allergy tests, such as skin prick tests, cause localized and temporary reactions at the test sites. During a skin prick test, a small amount of allergen extract is introduced to the skin’s surface, usually on the forearm or back, using a tiny device that barely penetrates the skin. If a person is allergic, a raised, red, and itchy bump, similar to a mosquito bite and called a wheal, appears within 15 to 20 minutes. These reactions are a normal part of the diagnostic process, indicating a positive response to the allergen, and subside within a few hours.

Patch testing, used to diagnose contact dermatitis, involves applying allergen-containing patches to the skin, often on the back, for 48 hours. Reactions to patch tests develop more slowly, with the skin being checked after 48 hours and again a few days later. A positive reaction appears as localized skin irritation, redness, or a rash under the patch. While these areas may be itchy or uncomfortable, they are temporary and indicate sensitivity to the tested substance.

Understanding Systemic Responses and Allergic Reactions

Beyond localized discomfort, allergy testing can, in rare instances, lead to systemic allergic reactions. A systemic reaction occurs when the immune system releases chemicals that cause symptoms far from the initial exposure site. These symptoms can include widespread hives or a rash, swelling of the face or throat, and respiratory difficulties like wheezing or shortness of breath.

Other signs of a systemic response might involve dizziness, lightheadedness, nausea, or vomiting. The most severe form of a systemic reaction is anaphylaxis, a rapid and potentially life-threatening event. While extremely rare during skin testing, anaphylaxis requires immediate medical attention. It can manifest as a sudden drop in blood pressure, severe breathing issues, or a combination of widespread symptoms.

When to Seek Medical Care After Allergy Testing

It is important to know when symptoms following allergy testing warrant medical attention. While mild, localized reactions are expected, any symptoms that are widespread, severe, or do not resolve quickly should be reported to your healthcare provider. For instance, if you develop a generalized rash or hives, or if symptoms at the test site worsen significantly.

Seek immediate emergency medical care if you experience difficulty breathing, wheezing, chest tightness, or a sudden onset of dizziness or lightheadedness. Swelling of the face, lips, or throat also indicates a more serious reaction that requires prompt evaluation. Contact your clinic or emergency services if any concerning or persistent symptoms arise after your allergy test.

Minimizing Risks During Allergy Testing

Healthcare providers implement several safety measures to minimize risks during allergy testing. Tests are conducted in a controlled environment where staff can closely monitor patients for any signs of adverse reactions. Clinics are equipped with emergency medications, including epinephrine, to promptly manage any severe systemic responses, such as anaphylaxis. This preparedness ensures that potential reactions can be addressed quickly and effectively.

Before testing, individuals are asked to provide a comprehensive medical history, including all current medications. It is important to disclose any medications, as these can interfere with test results or affect the body’s response during a reaction. Following these guidelines helps ensure the accuracy of the test and contributes to patient safety throughout the process.