Can a Myomectomy Cause Infertility?

Uterine fibroids, also known as leiomyomas, are non-cancerous growths that develop in the muscular wall of the uterus. These growths are very common, affecting many women during their reproductive years. For women trying to conceive, fibroids can pose a significant challenge to achieving or maintaining a pregnancy. Myomectomy is the surgical procedure designed to remove these fibroids while preserving the uterus. Although often recommended as a fertility-preserving treatment, the surgery introduces potential risks, raising the question of whether a myomectomy could inadvertently cause infertility.

How Fibroids Affect Fertility

Fibroids can interfere with reproductive function through several mechanisms that impact conception and implantation. The location of the fibroid is the most important factor determining its influence on fertility. Fibroids that protrude into the uterine cavity, known as submucosal fibroids, are the most likely to cause problems. They can distort the normal shape of the cavity, which is necessary for the successful attachment of an embryo.

Fibroids may also compromise the blood flow to the endometrium, which is the uterine lining where the embryo must implant. This decreased blood supply can reduce the receptivity of the lining, making it difficult for a fertilized egg to attach. In some cases, fibroids can physically block the openings of the fallopian tubes, preventing the egg and sperm from meeting for fertilization. Furthermore, the presence of fibroids, particularly large ones, is associated with a nearly doubled rate of miscarriage in the early stages of pregnancy. By creating a less favorable uterine environment, the growths can impede the ability to conceive or sustain a pregnancy.

Myomectomy’s Overall Effect on Fertility Outcomes

The primary objective of a myomectomy is to remove the mechanical obstruction caused by the fibroids and restore the uterus to a more normal shape. This restorative action generally leads to a significant improvement in fertility rates for women who struggled to conceive due to fibroids. Studies show that pregnancy rates can reach up to 70% following the procedure, especially in cases where the fibroids were distorting the uterine cavity. The removal of the fibroids improves endometrial receptivity, allowing for better embryo implantation and lowering the risk of subsequent miscarriage.

Despite these benefits, the surgery carries specific risks. Any incision into the uterus creates a site for scar tissue, or adhesions, to form outside the uterine wall. These adhesions can potentially bind the fallopian tubes or ovaries to other structures, interfering with the egg’s ability to travel and reducing the chance of conception. Another concern is the integrity of the uterine wall, especially after the removal of deep fibroids. The surgical repair can leave a weakened area that increases the risk of uterine rupture during a future pregnancy or labor, often necessitating a planned Cesarean delivery.

Surgical Approach and Fibroid Location as Risk Factors

The risk profile for fertility is heavily influenced by the surgical method used and the location and depth of the fibroids removed. For fibroids that bulge into the uterine cavity, a hysteroscopic myomectomy is often performed, which involves no external abdominal incision. This method is associated with the lowest risk of developing pelvic adhesions, making it the safest option for preserving future fertility.

Minimally invasive techniques, such as laparoscopic or robotic myomectomy, use small incisions and are employed for fibroids located in the wall or on the outer surface of the uterus. These approaches result in fewer adhesions compared to open abdominal myomectomy. However, deep intramural fibroids—those located within the muscular wall—require significant incisions into the uterine muscle, regardless of the surgical approach. This deep cutting poses a higher risk to the structural strength of the uterus. The surgeon’s layered suturing of the uterine defect is a significant factor in maintaining the uterus’s strength and minimizing future obstetric complications.

Post-Operative Recovery and Conception Timing

To maximize the chance of a safe and successful pregnancy after myomectomy, allowing the uterus to fully heal is paramount. The required waiting period before attempting conception depends on the extent of the uterine wall incision. For deep excisions into the uterine muscle, the healing time is typically longer to ensure the scar is strong enough to withstand the stresses of pregnancy.

A waiting period of three to six months is commonly advised after a laparoscopic myomectomy. Following an open abdominal myomectomy, the recommended waiting time is often six to twelve months due to the larger incision and deeper tissue repair. Attempting to conceive before the uterus has adequately healed significantly increases the risk of complications, particularly uterine rupture during later pregnancy stages. Following recovery, a follow-up appointment is necessary to confirm healing and discuss a tailored plan for conception.