Bifidobacterium longum BL999 is a specific and beneficial probiotic strain. As a probiotic, it involves live microorganisms that can confer health benefits when administered in adequate amounts. This strain offers targeted support for various bodily functions.
What is Bifidobacterium longum BL999
Bifidobacterium longum BL999 is a distinct strain belonging to the Bifidobacterium longum species, which is a common inhabitant of the mammalian gut, including humans and dogs. The “BL999” designation indicates it is a specific isolate, identified for its unique properties. This particular strain is formally recognized as Bifidobacterium longum ATCC BAA-999, signifying its registration in the American Type Culture Collection.
The Bifidobacterium longum species, including strain BL999, is a Gram-positive, anaerobic bacterium. It is one of the first bacterial species to colonize the human intestinal microbiome after birth. While its overall abundance can decrease with age, its presence is considered important for maintaining gut health throughout life.
Key Health Benefits
Bifidobacterium longum BL999 has been associated with several health benefits, particularly concerning the gut-brain axis and immune modulation. This strain can positively influence mood and behavior. For example, studies in anxious dogs demonstrated that supplementation with Bifidobacterium longum BL999 led to a significant reduction in anxiety-like behaviors (e.g., barking, jumping, spinning, pacing) and decreased stress markers like salivary cortisol.
Beyond its impact on mood, Bifidobacterium longum has been linked to improved digestive health and immune system support. It contributes to a balanced gut microbiome. In infants, specific formulations containing Bifidobacterium longum BL999 have shown promise in reducing the risk of developing eczema. This suggests a role in modulating immune responses, preventing certain allergic conditions.
Mechanism of Action
Bifidobacterium longum BL999 exerts its beneficial effects through several biological mechanisms. It primarily functions by modulating the gut microbiota, maintaining a healthy balance of microorganisms. It competes with harmful bacteria for nutrients and space, inhibiting pathogen growth and preventing the overgrowth of undesirable bacteria that can lead to gastrointestinal issues.
The strain also produces beneficial compounds, such as short-chain fatty acids (SCFAs) like lactic and acetic acid. These SCFAs lower the pH of the intestinal environment, creating conditions less favorable for pathogenic bacteria. Additionally, Bifidobacterium longum BL999 may strengthen the gut barrier function, which is a protective layer that prevents undesirable substances from entering the bloodstream. Its interactions with immune cells can also help modulate the body’s immune response, contributing to its overall health benefits.
Supplementation and Safety
Bifidobacterium longum BL999 is typically available in dietary supplements, often as part of a multi-strain probiotic blend. It can also be found in certain fortified foods. When considering supplementation, it is important to follow the product’s instructions regarding dosage, which can vary. For adults, doses of Bifidobacterium longum up to 20 billion colony-forming units (CFUs) daily have been used safely for up to eight weeks.
While generally well-tolerated, some individuals may experience mild digestive upset, such as gas or bloating, especially when first starting a probiotic supplement. It is advisable to consult a healthcare professional before beginning any new supplement, particularly for individuals with underlying health conditions, compromised immune systems, or those who are pregnant or nursing. In rare instances, particularly in critically ill infants, there have been reports of blood infections associated with Bifidobacterium longum, emphasizing the importance of medical guidance in vulnerable populations.