Why Is Only One of My Ankles Swollen?

Unilateral ankle swelling, or edema, means excess fluid has accumulated in one ankle. While swelling often occurs in both lower legs due to gravity, swelling in just one ankle can indicate either a minor, temporary issue or an underlying health concern requiring attention.

Everyday Reasons for Swelling in One Ankle

Minor injuries frequently cause swelling in a single ankle. A sprained ankle, where ligaments are stretched or torn, leads to immediate inflammation. Muscle strains or direct trauma also cause localized tissue damage and swelling as part of the body’s natural healing process.

Insect bites or stings can also trigger localized swelling. The body’s immune system reacts to the foreign substance, causing an inflammatory response with redness, warmth, and swelling. Though often itchy, the primary symptom is localized puffiness. These typically resolve with rest and basic care.

Prolonged standing or sitting, especially in positions restricting blood flow, can cause fluid to pool in the lower extremities, sometimes affecting one ankle more due to posture or circulation differences. Unusual physical activity or overuse can also contribute, as increased blood vessel pressure may cause fluid leakage. This swelling is generally temporary and improves with movement or elevation.

Underlying Health Issues Affecting One Ankle

More serious medical conditions can also manifest as unilateral ankle swelling, often requiring professional diagnosis and treatment. Deep Vein Thrombosis (DVT) is a condition where a blood clot forms in a deep vein, most commonly in the leg or thigh. This clot obstructs blood flow returning to the heart, causing blood to pool and resulting in swelling, pain, warmth, and sometimes discoloration in the affected leg or ankle. DVT is a significant concern because the clot can break loose and travel to the lungs, leading to a pulmonary embolism.

Cellulitis, a bacterial infection of the skin and underlying tissues, presents with localized swelling, redness, warmth, and tenderness in the affected area. Bacteria typically enter through a break in the skin, leading to a rapid inflammatory response. Without treatment, cellulitis can spread quickly and become a more severe infection.

Gout is a type of inflammatory arthritis caused by the buildup of uric acid crystals in a joint, frequently affecting the big toe but also common in the ankle. An ankle gout flare-up can cause sudden, intense pain, significant swelling, redness, and warmth in the joint. The swelling and pain can be so severe that even light touch is intolerable.

Certain types of arthritis, such as psoriatic arthritis, can also cause unilateral ankle swelling. Psoriatic arthritis involves the body’s immune system attacking the joint lining, leading to inflammation, pain, stiffness, and swelling. This condition can affect joints asymmetrically, meaning it might impact one ankle more significantly than the other, or even just one joint in the ankle.

Lymphedema results from a compromised lymphatic system, which normally drains excess fluid from tissues. If lymphatic vessels are blocked or damaged, lymph fluid accumulates, causing swelling that can be confined to one leg or ankle. This condition can be primary, due to inherited issues with the lymphatic system, or secondary, often resulting from surgery, radiation, or infection.

Venous insufficiency occurs when the valves in the leg veins do not function properly, allowing blood to pool in the lower extremities instead of returning efficiently to the heart. While it often affects both legs, it can be more pronounced or initially appear in one leg if the veins in that limb are more severely affected or damaged. This pooling of blood leads to fluid leakage into surrounding tissues, causing swelling, aching, and potentially skin changes.

When to Seek Professional Medical Advice

It is important to recognize when unilateral ankle swelling warrants medical attention. Seek immediate care if the swelling is sudden and severe, accompanied by intense pain, redness, or warmth, or if you develop a fever. Difficulty walking or bearing weight on the affected ankle is also a concerning sign.

If the swollen ankle appears pale or feels cold to the touch, or if you experience symptoms like shortness of breath or chest pain, these could indicate a serious condition such as a blood clot that has traveled to the lungs, requiring emergency medical help. Any persistent or worsening unilateral ankle swelling that does not improve with home care measures should be evaluated by a healthcare professional to determine the underlying cause and appropriate treatment.

Immediate Home Care Measures

For minor causes of unilateral ankle swelling, several home care measures can provide temporary relief. The R.I.C.E. protocol, which stands for Rest, Ice, Compression, and Elevation, is often recommended. Resting the affected ankle helps prevent further injury, while applying ice for 10-20 minutes at a time can reduce pain and inflammation. Using a compression bandage can help limit swelling by gently pushing fluid away from the area. Elevating the ankle above heart level aids in fluid drainage, reducing the accumulation of fluid in the limb.

Avoiding tight clothing or shoes can prevent further constriction and promote better circulation. These measures are designed for temporary relief and are not a substitute for professional medical diagnosis or treatment if an underlying condition is suspected.