Progesterone cream is a transdermal hormone therapy applied to the skin, allowing the hormone to be absorbed into the bloodstream to support fertility. Understanding optimal application methods and sites can help maximize its benefits.
Progesterone’s Role in Fertility Support
Progesterone is a hormone naturally produced by the ovaries, primarily after ovulation. It prepares the uterine lining, the endometrium, to receive and nurture a fertilized egg. This involves thickening the uterine lining, creating an environment supportive of implantation.
If a fertilized egg implants, progesterone levels continue to rise, helping to maintain the pregnancy and prevent uterine contractions. In cases of assisted reproductive technologies like in vitro fertilization (IVF), progesterone supplementation is often prescribed because certain medications can affect the body’s natural progesterone production.
Key Application Sites for Progesterone Cream
Progesterone cream is designed for transdermal absorption, meaning the hormone passes through the skin and into the bloodstream. For effective absorption, apply the cream to areas where the skin is thinner and has good blood flow, allowing for efficient hormone transfer.
Common application areas include the inner arms, inner thighs, abdomen, chest, and neck. Some sources also suggest areas like behind the knees, wrists, ankles, palms of the hands, and soles of the feet due to their thinner skin and capillary density. Applying the cream to areas above the navel may also help prevent rapid metabolism by the liver.
Optimizing Progesterone Cream Application
When applying the cream, rub the measured amount thoroughly into the chosen skin area for 60-120 seconds to ensure adequate absorption. The skin should be clean and dry before application, and it is advised to avoid lotions or oils beforehand, as they can interfere with absorption.
Rotating application sites daily is important to prevent saturation of progesterone levels in one area, which could reduce subsequent absorption. For fertility purposes, progesterone cream is typically used after ovulation, during the luteal phase of the menstrual cycle. It is generally started two to three days after ovulation and continued until menstruation begins or a pregnancy is confirmed. Starting progesterone before ovulation may inhibit the release of an egg.
Important Considerations for Safe Use
Absorption of progesterone through the skin can vary significantly among individuals, and the effectiveness of over-the-counter creams for fertility is a subject of ongoing discussion in research. The Food and Drug Administration (FDA) does not regulate many topical progesterone creams, especially those available over-the-counter.
Consult with a healthcare professional, such as a doctor or fertility specialist, before beginning or adjusting any progesterone cream regimen for fertility. A medical professional can provide guidance on appropriate dosage and timing, monitor hormone levels, and assess for potential side effects or interactions with other medications. Self-medication without professional oversight is not recommended, particularly when trying to conceive.