Testosterone replacement therapy (TRT) offers solutions for individuals experiencing low testosterone levels. Among various delivery methods, testosterone troches are a distinct option. This article clarifies what a testosterone troche is and how it functions within the body, exploring its composition, administration, and the conditions it addresses.
Defining Testosterone Troches
A testosterone troche is a small, medicated lozenge designed to deliver testosterone into the body. The term “troche” refers to a dosage form that dissolves slowly in the mouth, allowing for medication absorption. These lozenges combine testosterone with a base material for gradual release. Testosterone is a primary sex hormone, produced in the testes in men and in smaller amounts in women. It plays a role in various bodily functions, including male characteristics, bone density, muscle mass, sex drive, energy levels, and mood.
How Troches Deliver Testosterone
Testosterone troches work through mucosal absorption. When placed in the mouth, either under the tongue (sublingual) or between the cheek and gum (buccal), the troche slowly dissolves. Testosterone is then absorbed directly into the bloodstream through the oral lining’s blood vessels.
This method allows testosterone to bypass the digestive system and liver, avoiding first-pass metabolism. Bypassing the liver means more active hormone enters circulation compared to some oral tablet forms. While a significant portion absorbs directly, some may mix with saliva and be swallowed, potentially entering the digestive system. Troche delivery aims to provide a steady, consistent hormone release, though fluctuations can occur due to their short half-life.
Administering a Testosterone Troche
Administering a testosterone troche is a straightforward process to maximize absorption. The troche is typically placed in the mouth, either under the tongue or in the cheek cavity. It must dissolve naturally and completely, which usually takes 15 to 30 minutes.
To ensure proper absorption, avoid eating or drinking immediately before or after placement. Rotating the troche’s placement to different mouth areas with each dose can improve absorption and prevent localized irritation. Do not chew or swallow the troche whole before it has fully dissolved.
Who Might Use a Testosterone Troche
Testosterone troches are primarily used for individuals with diagnosed testosterone deficiency, also known as hypogonadism or “low T.” This condition occurs when the body does not produce enough testosterone. Symptoms that might lead a healthcare provider to consider testosterone replacement therapy include persistent fatigue, decreased libido, changes in mood, and reduced muscle mass.
Troches are prescription medications requiring a medical diagnosis. A healthcare provider typically conducts blood tests to confirm low testosterone levels and assess symptoms before prescribing TRT. Ongoing medical supervision monitors hormone levels and manages potential treatment effects.
The Role of Compounding in Troche Formulation
A distinctive aspect of testosterone troches is their frequent formulation by compounding pharmacies. Compounding involves custom preparation of medications to meet individual patient needs. This allows for precise tailoring of testosterone dosage and strength, beneficial for patients requiring amounts not available commercially.
Compounding pharmacies can also customize troches with specific flavors to improve patient acceptance and adherence. The ability to adjust formulations, including combining multiple hormones in a single troche, offers flexibility for complex hormone replacement regimens.