What Is a Blown Pupil and What Causes One?

A “blown pupil” describes an eye condition where one or both pupils appear unusually large and do not respond to light. This phenomenon is often a sign that warrants immediate medical attention, signaling a possible underlying health issue. Understanding its nature, origins, and appropriate response is important.

Understanding a Blown Pupil

A blown pupil is significantly dilated and fixed, meaning it does not constrict or react to light. Normally, pupils expand in low light to allow more light to enter and contract in bright light to limit light entry, a process controlled by the iris muscles. When a pupil is blown, these muscles are dysfunctional, leading to persistent enlargement.

Medically, general pupil dilation is termed mydriasis. When one pupil is larger than the other, this is known as anisocoria. To an observer, a blown pupil appears as a noticeably larger black circle in the center of the eye, which remains wide even in bright environments.

Underlying Causes

The reasons a pupil might become blown are diverse, ranging from neurological emergencies to specific eye conditions and external factors. Neurological emergencies frequently cause a blown pupil due to pressure on nerves that control pupil function.

Head trauma, such as an epidural hematoma, can lead to uncal herniation, compressing the oculomotor nerve (third cranial nerve) and causing the pupil to dilate and become unresponsive. Conditions like stroke, brain tumors, and aneurysms can also exert pressure on this nerve, resulting in similar pupillary changes.

Eye-specific conditions can also contribute to a blown pupil. Acute angle-closure glaucoma, characterized by a sudden increase in eye pressure, can affect the iris and lead to dilation. Direct trauma to the eye can damage the iris muscles, causing the pupil to dilate and lose its reactivity.

Certain medications and substances are known to induce pupil dilation. Ophthalmic drops containing agents like atropine or scopolamine, used for eye exams or other medical purposes, can temporarily dilate pupils. Recreational drugs such as cocaine, amphetamines, MDMA, and hallucinogens like LSD can also cause mydriasis by affecting the nervous system’s control over iris muscles. Accidental exposure to certain plants containing anticholinergic compounds can similarly lead to pupil dilation.

Other rare conditions can present with a dilated pupil. Adie’s pupil, a neurological disorder, typically causes one pupil to be larger and slowly reactive to light due to nerve damage behind the eye. Third nerve palsy, which can result from various causes including aneurysms, often involves a dilated pupil along with impaired eye movement and a drooping eyelid.

When to Seek Medical Help

A newly appearing blown pupil, whether in one or both eyes, that does not react to light is almost always a medical emergency requiring immediate medical attention. Accompanying symptoms further emphasize the need for urgent care.

These may include a severe headache, confusion, or a decreased level of consciousness. Weakness or numbness on one side of the body, sudden vision changes like double vision, nausea, or vomiting alongside a blown pupil also indicate a potentially serious condition. Any recent head injury combined with a dilated, unresponsive pupil should prompt immediate medical assessment.

Medical Evaluation and Care

Medical evaluation for a blown pupil involves a comprehensive assessment to identify the underlying cause. Healthcare professionals will perform a thorough neurological examination to check reflexes, coordination, and mental status. An eye examination, including checking pupil reactivity and eye movements, is also a standard part of the evaluation.

Imaging tests, such as a CT scan or MRI of the brain, are often utilized to visualize the brain and surrounding structures for abnormalities like blood clots, tumors, or swelling. Treatment for a blown pupil focuses on addressing the root cause, which could range from discontinuing certain medications to emergency surgery for conditions like brain aneurysms or severe head trauma. In some cases, if the cause is benign, treatment might involve managing symptoms like light sensitivity with sunglasses.