What Causes Inflammation of the Eyelids?

Eyelid inflammation, or blepharitis, is a frequent condition affecting the eyelids. It manifests as redness, irritation, and swelling of the eyelid margins. Understanding its causes aids effective management.

What is Eyelid Inflammation?

This condition often leads to symptoms such as itching, a burning sensation, and a gritty feeling, as if something is in the eye. Other common signs include flaking skin and crusting around the eyelashes, particularly noticeable upon waking.

Blepharitis can affect different parts of the eyelid. Anterior blepharitis impacts the outside front of the eyelid where the eyelashes attach. In contrast, posterior blepharitis affects the inner eyelid margin, where the oil-producing meibomian glands are located. Both types can occur simultaneously, contributing to discomfort.

Infectious and Parasitic Origins

Microorganisms contribute to eyelid inflammation. Bacteria, especially Staphylococcus species, can colonize the eyelid margins. These bacteria release toxins and enzymes that irritate the eyelid tissue. This irritation often results in crusting and flaking along the lash line.

Another cause involves microscopic Demodex mites. These mites typically live in or near hair follicles and sebaceous glands, including the eyelids. While a small number are normal, an overgrowth can trigger inflammation, itching, and eyelash abnormalities. Their presence can lead to symptoms like crusty flake buildup around the eyelashes, known as collarettes, or eyelash loss.

Allergic and Environmental Triggers

Non-infectious external factors also play a significant role in eyelid inflammation. Allergic reactions can occur from direct contact with substances like makeup, skincare products, contact lens solutions, or eyedrops. Airborne allergens, such as pollen, dust mites, or pet dander, can also trigger an immune response. This type of allergic reaction often causes intense itching and swelling of the eyelids.

Environmental irritants can also affect eyelid skin. Exposure to smoke, air pollution, or excessive dust can lead to irritation and inflammation. Additionally, conditions such as dry air or wind can contribute to eyelid irritation, exacerbating blepharitis. Avoiding these triggers can help reduce the frequency and severity of inflammation.

Systemic Health Contributions

Underlying health conditions can contribute to eyelid inflammation. Seborrheic dermatitis, a common skin condition, can extend from the scalp or eyebrows to the eyelids. This can result in oily, flaky, and inflamed eyelid margins.

Ocular rosacea, a form of rosacea, often affects the eyes and eyelids. It can cause eyelid inflammation and redness along the eyelid margins.

Chronic dry eye syndrome can irritate the ocular surface, leading to eyelid inflammation. Conversely, eyelid inflammation can worsen dry eye symptoms, creating a cycle of discomfort.