What Causes an Outbreak of Canker Sores?

Canker sores, also known as aphthous ulcers, are small, painful lesions that typically emerge on the soft tissues inside the mouth. These include the inner lining of the cheeks and lips, the tongue, and the soft palate. They are not contagious and usually resolve on their own within one to two weeks. Understanding the factors that contribute to their appearance can help manage these common oral discomforts.

Common Triggers

Physical trauma is a frequent initiator of canker sores, often occurring from accidental bites to the cheek or lip, aggressive tooth brushing, or irritation from dental work. Even minor abrasions or pressure points from orthodontic appliances can disrupt the delicate oral lining, leading to a sore.

Certain dietary components can also provoke outbreaks. Acidic foods such as citrus fruits, tomatoes, and some spicy foods are known to irritate the oral mucosa, potentially triggering a canker sore in susceptible individuals. Chocolate and coffee have also been implicated by some as dietary triggers.

Emotional stress and insufficient sleep are recognized factors that can weaken the body’s resilience, making individuals more prone to developing canker sores. Prolonged periods of high stress levels may influence the immune system, indirectly contributing to the onset of these lesions.

Deficiencies in certain vitamins and minerals, including iron, folate, zinc, or vitamin B12, can also play a role in the formation of canker sores. These micronutrients are important for maintaining healthy oral tissues and immune function.

Some oral care products contain sodium lauryl sulfate (SLS), a foaming agent that has been linked to canker sore outbreaks in some individuals. This detergent can strip away the protective lining of the mouth, making it more vulnerable to irritation and lesion formation. Switching to an SLS-free toothpaste may reduce the frequency of sores for those sensitive to the ingredient. Furthermore, hormonal fluctuations, particularly those experienced by women during menstrual cycles, are sometimes associated with increased canker sore activity, suggesting a systemic influence on oral health.

Underlying Predisposing Factors

Genetic predisposition plays a significant role in an individual’s susceptibility to canker sores. If one or both parents frequently experience these lesions, their children are often more likely to develop them, indicating a hereditary component.

The immune system’s state also influences canker sore development. An immune system that is either compromised or overactive can contribute to outbreaks.

Certain medical conditions are linked with an increased incidence of canker sores. Conditions such as Celiac disease, inflammatory bowel diseases like Crohn’s disease and ulcerative colitis, and Behcet’s disease often present with oral lesions, including canker sores, as part of their systemic manifestations. These underlying health issues can create an environment where the oral mucosa is more vulnerable. Moreover, some medications, including certain non-steroidal anti-inflammatory drugs (NSAIDs) and beta-blockers, have been observed to increase susceptibility to canker sores as a side effect.

Distinguishing Canker Sores from Other Oral Lesions

Canker sores typically manifest on the soft, movable tissues inside the mouth, such as the inner cheeks, lips, tongue, and the soft palate. This location differentiates them from cold sores (herpes labialis), which usually appear outside the mouth, often on or around the lips.

Another important distinction is their non-contagious nature; canker sores cannot be spread from person to person. This contrasts sharply with viral lesions like cold sores, which are highly contagious.

Canker sores usually present as round or oval lesions with a white or yellowish center and a distinct red border. Their appearance is generally consistent, aiding in identification. While other oral issues, such as irritation from sharp teeth or certain cancerous lesions, can occur in the mouth, canker sores typically resolve spontaneously within a few weeks without intervention, unlike more serious conditions that persist or worsen.

When to Seek Professional Medical Advice

It is advisable to consult a healthcare professional if a canker sore is unusually large or painful, causing significant difficulty with eating or drinking.

Medical advice should also be sought if a sore does not heal within two to three weeks, or if new sores appear frequently and are difficult to manage.

If canker sores are accompanied by other systemic symptoms, such as a fever, diarrhea, headache, or a skin rash, it is important to seek medical attention.