What Are the Signs and Symptoms of Hookworm?

Hookworm is a parasitic infection caused by roundworms living in the human intestines. These parasites are prevalent globally, particularly in tropical and subtropical regions where sanitation may be limited and people often walk barefoot. Understanding the signs of hookworm is important for early detection and intervention.

Initial Manifestations of Infection

The first indications of hookworm infection often appear on the skin where larvae penetrate. This initial reaction, known as “ground itch” or cutaneous larva migrans, manifests as an intensely itchy, red rash or small, raised blisters, typically on the feet or hands.

The larvae burrow into the upper layers of the skin, causing a tingling or prickling sensation. This can create visible, snake-like tracks as the larvae migrate beneath the skin’s surface. While these animal hookworm larvae cannot mature in humans and eventually die, the skin irritation can persist for several weeks.

Gastrointestinal and Systemic Indicators

Once hookworm larvae mature and establish themselves in the intestines, they can lead to gastrointestinal and systemic issues. Common digestive complaints include abdominal pain, cramping, nausea, vomiting, diarrhea, and a reduced appetite. Some individuals might also experience unintended weight loss.

A significant systemic consequence of hookworm infection is iron deficiency anemia, resulting from the worms feeding on blood from the intestinal walls. This anemia can manifest as persistent fatigue, generalized weakness, and pale skin. Other signs include shortness of breath, dizziness, and sometimes pica, a craving for non-food items like dirt or ice. In severe cases, sustained blood loss can also lead to protein deficiency and heart problems.

Signs in Vulnerable Populations

Hookworm infection can have more pronounced and severe effects in vulnerable populations, particularly children and pregnant women. In children, chronic hookworm infection and the resulting anemia can hinder physical growth and contribute to developmental delays. The iron loss can also impair cognitive function, affecting school performance and learning abilities.

Pregnant women face an increased risk of severe anemia due to hookworm infection, especially given the heightened demand for nutrients during pregnancy. This can lead to complications such as low birth weight and premature delivery, impacting both maternal and infant health.

When to Consult a Healthcare Professional

It is advisable to consult a healthcare professional if any described symptoms are present, particularly if persistent or worsening. Early diagnosis and appropriate treatment are important for preventing long-term complications, such as severe anemia and its associated health issues.

A healthcare provider typically diagnoses hookworm infection by examining a stool sample under a microscope for hookworm eggs. Blood tests can also indicate signs of anemia or an elevated white blood cell count (eosinophilia), which can suggest a parasitic infection. Prompt medical attention helps ensure effective management and recovery.