Spiders That Are Venomous to People

While almost all spider species produce venom, this chemical weapon is primarily used to subdue their insect prey or as a defense mechanism. Only a small percentage of the nearly 50,000 known spider species possess venom potent enough to cause medically significant reactions in humans.

The Nature of Spider Venom

Spider venom is a complex mixture of chemical compounds, including salts, carbohydrates, amino acids, and polyamines. The primary active components are typically peptides and proteins, many of which are neurotoxins. Neurotoxins target insect nervous systems, causing paralysis. Some venoms also contain cytolytic peptides, which can damage cells and tissues.

Spiders deliver venom through their fangs, but potency and quantity vary greatly among species. Most spider venoms are not formulated to significantly affect the human nervous system, or the amount delivered is too small to cause serious harm. Many venom components are highly specific to invertebrate physiology, which is why most spider bites result in only minor, localized reactions.

Widely Known Venomous Spiders

The black widow spiders (genus Latrodectus) are identified by a red hourglass marking on the underside of their abdomen. Found worldwide in outdoor debris, woodpiles, and dark, undisturbed areas, their venom is neurotoxic, affecting the nervous system.

Brown recluse spiders (Loxosceles reclusa) are a concern, particularly in the south-central United States. They have a violin-shaped marking on their back. These spiders prefer secluded, dry areas like wood or rock piles outdoors, and dark closets or attics indoors. Their venom is cytotoxic, capable of damaging tissues.

The Sydney funnel-web spider (Atrax robustus) is native to Australia and considered one of the most dangerous spiders globally. These large, black spiders construct funnel-shaped webs in moist, cool, and sheltered places. Their neurotoxic venom can rapidly cause severe systemic effects. Brazilian wandering spiders (genus Phoneutria), sometimes called “banana spiders,” are found in South and Central America and are also highly venomous. These fast-moving spiders possess potent neurotoxic venom.

Identifying a Spider Bite

Identifying a spider bite can be challenging because many other insect bites or skin conditions resemble them. Many spider bites cause only minor irritation, appearing as a red, inflamed, or itchy bump. The bite itself is often not immediately felt. If a spider bite is suspected, observing the development of symptoms is more reliable than trying to identify the spider.

Bites from medically significant spiders, such as the black widow, often begin with sharp pain, followed by muscle cramps that spread from the bite site. These cramps can affect the abdomen, back, or chest, and may be accompanied by nausea, vomiting, sweating, and headache. Brown recluse bites may initially be painless or cause a stinging sensation, with pain and itching developing hours later. The bite area can become red and tender, potentially developing a blister that may rupture into an open sore, sometimes described as a “bull’s-eye” lesion. Systemic symptoms like fever, chills, and body aches can also occur. Funnel-web and Brazilian wandering spider bites typically cause immediate, severe pain at the site. Systemic effects can rapidly develop, including profuse sweating, nausea, vomiting, muscle spasms, and breathing difficulties.

Bite Management and Prevention

If a spider bite occurs, immediate first aid steps can help manage the reaction. Clean the bite area with mild soap and water to prevent infection. Apply a cool compress or ice pack regularly to reduce pain and swelling. Elevating the affected limb helps minimize swelling. Over-the-counter pain relievers can alleviate discomfort, and antihistamines may reduce itching.

Seek professional medical attention if you suspect a bite from a black widow, brown recluse, or other dangerous spider, or if symptoms worsen. Signs indicating a need for medical evaluation include spreading redness, severe pain, muscle cramping, fever, chills, nausea, vomiting, or if the bite develops into an open wound or blister. Children, the elderly, or individuals with compromised immune systems bitten by a potentially venomous spider should receive immediate medical care.

Preventing spider bites involves reducing contact with spiders and making your environment less appealing to them.

  • Shake out clothing, towels, and shoes before use.
  • Wear gloves when working in areas where spiders might hide, such as woodpiles, garages, or crawl spaces.
  • Seal cracks and crevices in your home to prevent spiders from entering.
  • Reduce clutter, keep bedding away from walls, and store items off the floor in sealed containers to minimize indoor hiding spots.