Robenacoxib, known by its brand name Onsior, is a non-steroidal anti-inflammatory drug (NSAID) specifically developed for feline use. This medication is available by prescription only and manages pain and reduces inflammation in cats.
Conditions Treated with Robenacoxib
Veterinarians prescribe robenacoxib for acute pain and inflammation, especially after surgery. It is FDA-approved for postoperative pain and inflammation from orthopedic surgeries (e.g., broken bones) and soft tissue surgeries (e.g., spaying, neutering, dental extractions). The medication offers a rapid onset of action, within 30 minutes, providing prompt pain relief.
Beyond surgical recovery, robenacoxib also manages pain and inflammation from acute musculoskeletal disorders, including injuries to muscles, ligaments, or joints. While primarily approved for short-term use, some veterinarians may prescribe it off-label for chronic pain conditions like osteoarthritis, with careful monitoring. This extended use can improve a cat’s comfort and mobility.
Dosage and Administration
Robenacoxib is available in two forms for cats: oral tablets and an injectable solution. The injectable form is often administered by a veterinarian, such as prior to surgery. Oral tablets, which are flavored, are typically given at home for continued pain management.
The dosage of robenacoxib is determined by the cat’s body weight, with a recommendation of 0.45 mg per pound (1 mg/kg) orally once daily. For example, a cat weighing 5.5 to 13.2 lbs receives one 6 mg tablet, while larger cats (13.3 to 26.4 lbs) receive two 6 mg tablets daily. Administer tablets whole; they are not scored and should not be broken or crushed, as this could affect the absorbed dosage.
Robenacoxib can be given with or without food; administering it on an empty stomach may lead to faster absorption. If digestive upset occurs without food, it can be given with a small meal to help mitigate these effects. The medication is intended for short-term use, with FDA approval for a maximum of three consecutive days for postoperative pain. Owners should strictly adhere to the veterinarian’s instructions regarding treatment duration.
Potential Side Effects and Safety Precautions
While generally well-tolerated, robenacoxib can cause side effects, similar to other NSAIDs. Common reactions include transient diarrhea, soft stool, decreased appetite, and vomiting. Some cats may also experience lethargy or depression. These effects resolve once the medication is discontinued.
More serious, though less common, side effects can occur and necessitate immediate veterinary attention. These include signs such as severe lethargy, jaundice (yellowing of the gums, skin, or whites of the eyes), or dark, tarry stools, which may indicate gastrointestinal bleeding. Other concerning signs are increased thirst or urination, changes in behavior, incoordination, or seizures. Owners should also watch for bleeding or infection at the surgical incision site if the medication is given post-surgery.
Robenacoxib should not be administered to cats with a known hypersensitivity to the drug or other NSAIDs. It is also contraindicated in cats with pre-existing conditions affecting the gastrointestinal tract, such as ulcers. Avoid use or use with caution in cats with impaired kidney, liver, or heart function, or those that are dehydrated or have low blood pressure. Pregnant or lactating cats should not receive robenacoxib, as its safety in these animals has not been established. If adverse reactions are suspected, stop administering the medication and contact your veterinarian immediately.