Permixon 160 mg is a standardized extract derived from the fruit of the Saw Palmetto plant (Serenoa repens). This medication is a lipidosterolic extract containing fatty acids and plant sterols. It is formulated into capsules, each containing 160 milligrams of the active extract. The medication is used to address certain health concerns in men.
Treating Benign Prostatic Hyperplasia
As men age, the prostate gland can enlarge, a common non-cancerous condition known as Benign Prostatic Hyperplasia (BPH). This enlargement can press on the urethra, the tube that carries urine from the bladder, leading to various uncomfortable urinary issues. Common symptoms include a frequent need to urinate, especially at night, a weakened or interrupted urine stream, and a sensation of incomplete bladder emptying.
Permixon 160 mg is indicated for symptomatic treatment of moderate urinary disorders associated with BPH. It aims to alleviate bothersome symptoms, such as frequent urination and a weakened urinary stream. Addressing these symptoms can improve quality of life for men with BPH.
Studies show Permixon enhances urinary flow rates, making bladder emptying easier. It also reduces nighttime urination frequency, with reported reductions ranging from 33% to 74%. Improvements in daytime urinary frequency and peak urinary flow rate are also observed.
Understanding Its Action
Permixon 160 mg’s therapeutic effects in BPH are attributed to several mechanisms within the prostate. It primarily influences hormone metabolism. The lipidosterolic extract inhibits both type 1 and type 2 isoenzymes of 5-alpha-reductase, an enzyme converting testosterone into dihydrotestosterone (DHT).
Dihydrotestosterone is a potent androgen that plays a role in prostate growth. By interfering with DHT production, Permixon may reduce hormonal stimulation contributing to prostate enlargement. The extract also interferes with DHT binding to androgen receptors within prostate cells, further moderating its effects.
Permixon also possesses anti-inflammatory properties. Prostate inflammation can contribute to BPH symptoms; reducing this inflammation may alleviate discomfort and improve urinary function. These combined actions contribute to symptomatic relief in men with BPH.
Important Usage Information
For adult men, the typical dosage of Permixon 160 mg is one capsule taken twice daily. It is recommended to take the capsules with meals to minimize potential digestive upset, such as nausea. Adhering to the prescribed dosage and administration instructions is important for optimal results.
While some men may experience relief relatively quickly, the full benefits of Permixon may not be immediate and can take several weeks or months to become apparent. During treatment, regular medical monitoring of the prostate is advised, as Permixon cannot replace surgical intervention when it is deemed necessary.
Like all medications, Permixon 160 mg can cause side effects, though not everyone experiences them. Common mild side effects include headache and abdominal pain. Less common effects may involve nausea, skin rash, or temporary increases in liver enzymes. In rare instances, abnormal breast development in men, known as gynecomastia, has been reported, which is typically reversible upon stopping the treatment.
It is important to consult a healthcare professional before starting Permixon, especially if taking other medications, to discuss potential interactions or suitability. This medication is not indicated for women or children. In cases of accidental overdose, which may lead to transient digestive disturbances, medical advice should be sought.