Is Dextromethorphan Safe to Take When Pregnant?

When experiencing a cough during pregnancy, individuals seek relief while prioritizing their baby’s well-being. Dextromethorphan, a common ingredient in over-the-counter cough medicines, raises questions about its safety. Understanding its properties and current medical guidelines is important for informed decisions and safe symptom management.

About Dextromethorphan

Dextromethorphan (DM) is a synthetic, non-narcotic cough suppressant. It works by affecting the brain’s cough reflex, reducing the frequency and intensity of coughing episodes. DM is commonly found in over-the-counter (OTC) cough and cold preparations, either as a single ingredient or in combination with other medications.

Pregnancy Safety Guidelines

Medical organizations generally consider dextromethorphan low risk for use during pregnancy, though consulting a healthcare provider is always advised. Research has not shown an increased risk of major malformations above the typical background rate of 1% to 3% in pregnancies where dextromethorphan was used in the first trimester. One large study explored a potential link between DM and birth defects, but mothers often used other medications, making DM’s role unclear. Still, the study authors considered DM generally safe.

It is recommended to use the lowest effective dose for the shortest duration necessary to relieve symptoms. While some sources suggest it may be considered safe throughout pregnancy, others advise its use particularly after the first trimester (after 12 weeks). This cautious approach aligns with general guidelines for medication use during pregnancy, where non-medication options are preferred first.

Choose single-ingredient products containing only dextromethorphan, avoiding combination cold medications that may include less safe substances. Avoid products containing alcohol, as it is unsafe during pregnancy. No medication is entirely without risk, and individual circumstances or health conditions can influence recommendations. Discuss medication use with a prenatal care team or pharmacist to ensure safety for both the pregnant individual and the baby.

Alternative Cough Remedies

For pregnant individuals seeking cough relief, several non-pharmacological and alternative options are recommended. Staying well-hydrated with fluids like water, herbal teas, and clear broths helps loosen mucus and soothe the throat. Warm liquids with honey and lemon are effective for soothing a sore throat. Honey itself can help clear mucus and soothe the throat.

Using a humidifier adds moisture to the air, helping alleviate throat irritation and dry coughs, especially at night. Gargling with warm salt water can reduce throat irritation and discomfort. Saline nasal sprays are beneficial if the cough is linked to post-nasal drip or congestion. Cough drops, including menthol and non-menthol options, are generally considered safe during pregnancy for soothing effects.

Urgent Medical Consultation

Certain cough symptoms warrant immediate medical attention during pregnancy. Contact a doctor if a cough persists for more than a few days without improvement, or if symptoms worsen. A high fever (typically over 101.5°F/38.6°C), or one lasting more than a day or two, should prompt a call to the healthcare provider.

Difficulty breathing, shortness of breath, wheezing, or chest pain are serious symptoms that require prompt medical evaluation. Coughing up discolored mucus (such as green, yellow, or bloody phlegm) signals a need for medical advice. Any concerns about medications already taken, or if the cough prevents eating or sleeping, should also be discussed with a healthcare provider.