How to Help Stomach Pain From Antibiotics

Antibiotics effectively treat bacterial infections but can cause uncomfortable side effects, including stomach pain. This article provides practical guidance for managing antibiotic-related stomach discomfort.

How Antibiotics Affect Digestion

Antibiotics work by targeting and eliminating bacteria, including beneficial gut bacteria. This disruption of the natural balance of microorganisms in the digestive tract can lead to various gastrointestinal issues, including pain, nausea, cramping, and diarrhea. Some antibiotics may also directly irritate the stomach lining, contributing to abdominal discomfort. This imbalance, known as dysbiosis, can persist for a significant time after antibiotic exposure.

Quick Relief Measures

Immediate steps can help alleviate existing stomach pain caused by antibiotics. Eating small, bland meals throughout the day can be gentler on the digestive system compared to large, heavy ones. Staying well-hydrated by drinking plenty of water helps flush the digestive system and can reduce symptoms like constipation and stomach discomfort. It is often beneficial to avoid foods that can irritate the stomach, such as spicy, acidic, high-sugar, or fatty foods, while experiencing pain. If your antibiotic prescription indicates it, taking the medication with food can sometimes lessen gastrointestinal distress.

Dietary Approaches and Probiotics

Dietary adjustments can support gut health during and after antibiotic treatment. Incorporating fermented foods like yogurt, kefir, sauerkraut, kimchi, and miso can introduce beneficial bacteria, such as Lactobacilli, to help restore gut microbiota. While fiber-rich foods are generally beneficial for gut health, it is often recommended to consume them after finishing an antibiotic course, as fiber can sometimes reduce antibiotic absorption. Prebiotic foods, indigestible carbohydrates found in items like onions, garlic, asparagus, and bananas, feed the good bacteria in the gut.

Probiotics, which are live microorganisms, can help restore the natural balance of bacteria in the gut disrupted by antibiotics. Specific strains, such as Lactobacillus rhamnosus GG and Saccharomyces boulardii, are frequently recommended for preventing antibiotic-associated diarrhea. For optimal benefit, probiotics are typically taken at least two hours before or after an antibiotic dose to prevent the antibiotic from killing the probiotic bacteria. Recommended daily dosages often range from 5 to 40 billion colony-forming units (CFUs). Continuing probiotic supplementation for at least two weeks after completing the antibiotic course can further support gut recovery.

Knowing When to Seek Medical Advice

While stomach pain from antibiotics is common, certain symptoms warrant prompt medical attention. Severe abdominal pain, especially if persistent or worsening, should be evaluated by a healthcare professional. Other concerning signs include high fever, bloody stools, or diarrhea that does not improve after a few days or becomes severe. These symptoms could indicate a more serious condition, such as a Clostridioides difficile infection. Additionally, watch for signs of an allergic reaction to the antibiotic, such as a rash, hives, swelling of the face, lips, tongue, or throat, wheezing, or difficulty breathing, which require immediate medical care.