How Do I Use Oxymetazoline Nasal Spray?

Oxymetazoline nasal spray is an over-the-counter medication that relieves nasal congestion. It constricts blood vessels in the nasal passages, reducing swelling and improving airflow. Its primary purpose is temporary relief from stuffiness caused by the common cold, seasonal allergies, or sinusitis.

Using Oxymetazoline Nasal Spray Effectively

Before use, wash your hands. Gently blow your nose to clear mucus, helping the medication reach the nasal lining. If the bottle is new or unused, prime the pump by spraying into the air until a fine mist appears. This ensures a full, even dose.

When applying, tilt your head slightly forward to prevent medication from draining down your throat. Insert the nozzle into one nostril, not too deep. Aim the tip slightly away from the septum to prevent irritation. Press the pump firmly, gently inhaling through your nose to draw the medication further in.

After spraying, remove the nozzle and repeat for the other nostril if directed. Wipe the nozzle clean with a tissue and replace the cap. Each bottle should only be used by one person to prevent germ spread.

Proper Dosage and Treatment Duration

For adults and children over six, the recommended dosage is two or three sprays into each nostril. Repeat every 10 to 12 hours, as needed, for nasal congestion. Do not exceed two doses within a 24-hour period.

Oxymetazoline nasal spray should not be used for more than three consecutive days. Prolonged use can lead to rebound congestion (Rhinitis Medicamentosa). This occurs when nasal passages become dependent on the medication’s constrictive effect. As the medication wears off, blood vessels in the nose can swell more than before, causing worse congestion.

Rebound congestion creates a cycle where the nose becomes increasingly blocked, prompting more frequent spray use, which exacerbates swelling. To avoid this, discontinue use after three days, even if congestion persists. If a dose is missed, apply it as soon as you remember; do not double the dose.

Important Safety Guidelines

Individuals with certain medical conditions should use caution or avoid oxymetazoline nasal spray without consulting a healthcare professional. Conditions like high blood pressure, heart disease, thyroid disorders, diabetes, glaucoma, or an enlarged prostate can be affected by decongestants. People taking monoamine oxidase (MAO) inhibitors, or who stopped them within the last 14 days, should also avoid this medication. Discuss your medical history and current medications with a doctor or pharmacist before treatment.

Mild side effects may occur, including temporary burning, stinging, or dryness in the nasal passages. Sneezing after application is also possible. These effects are usually brief, resolve quickly, and do not typically require medical attention.

More serious side effects require immediate medical attention. These include dizziness, nausea, insomnia, or increased anxiety. Irregular or fast heartbeat, or difficulty urinating are also concerning symptoms. If nasal congestion worsens, does not improve after three days, or if severe side effects develop, seek medical advice promptly.

Store oxymetazoline nasal spray at room temperature, away from direct light and excessive moisture. Avoid freezing. Keep the spray out of reach of children to prevent accidental ingestion, as small amounts can cause serious reactions. In case of overdose or child ingestion, seek emergency medical help immediately.