Espiran is a medication commonly prescribed to manage pain and inflammation associated with various conditions. Understanding how this medication works, its appropriate uses, and important safety considerations is important for anyone considering or currently taking it. This overview provides essential information regarding Espiran to help patients make informed decisions about their treatment.
What is Espiran and How Does It Work
Espiran contains etoricoxib, a non-steroidal anti-inflammatory drug (NSAID). It is a selective cyclooxygenase-2 (COX-2) inhibitor, meaning it primarily targets the COX-2 enzyme. This enzyme plays a significant role in the body’s inflammatory response. By selectively blocking COX-2, Espiran reduces the production of prostaglandins, chemicals that cause pain, swelling, and fever.
This selective action helps minimize gastrointestinal side effects often associated with non-selective NSAIDs. Espiran works to reduce inflammation and pain in the joints and muscles, offering relief for various painful conditions.
Recommended Uses and Dosage
Espiran is commonly prescribed to relieve pain and inflammation in adults 16 years and older. It is used for chronic conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It also provides short-term relief for acute gouty arthritis and moderate pain following dental surgery. For osteoarthritis, a typical dose is 30 mg or 60 mg once daily. Rheumatoid arthritis and ankylosing spondylitis may involve doses of 60 mg or 90 mg once daily.
For acute gout, 120 mg once daily for up to eight days is often prescribed. Following dental surgery, 90 mg once daily for up to three days is common. Espiran can be taken with or without food. Always follow a healthcare professional’s specific dosage instructions, as the appropriate dose depends on the treated condition and individual patient needs.
Potential Side Effects
Like all medications, Espiran can cause side effects, some common and generally mild. These include gastrointestinal issues such as stomach discomfort, abdominal pain, indigestion, nausea, vomiting, or diarrhea. Headaches and dizziness are also reported. Some individuals may experience fluid retention, leading to swelling in the legs or feet, and an increase in blood pressure.
More serious side effects require immediate medical attention. These include severe stomach pain, black stools, or blood in vomit, indicating gastrointestinal bleeding. Cardiovascular events like heart attack or stroke are possible, especially with higher doses or prolonged use. Liver problems, characterized by yellowing skin or eyes, dark urine, or severe abdominal pain, also require prompt medical evaluation.
Important Precautions and Warnings
Espiran requires caution, and some individuals should avoid it entirely. It is contraindicated for patients with a history of NSAID allergies, active peptic ulcers, or gastrointestinal hemorrhage. Patients with uncompensated heart failure, uncontrolled high blood pressure, ischemic heart disease, or cerebrovascular disease should not take Espiran due to increased cardiovascular risk. It is not recommended for those under 16 years of age.
Inform your doctor about kidney or liver problems, dehydration, or a history of stomach bleeding or ulcers before starting Espiran. Espiran can interact with other medications, including blood thinners, other NSAIDs, and certain blood pressure medications, potentially increasing risks or reducing effectiveness. Pregnant or breastfeeding individuals should consult their doctor; Espiran is not recommended during pregnancy, especially in the third trimester, and its presence in breast milk is not fully known.