Does SIBO Cause Gastritis? Examining the Relationship

Small Intestinal Bacterial Overgrowth (SIBO) and gastritis are two common digestive conditions that can significantly impact well-being. Given their shared impact on the digestive system, many people wonder if these two conditions are linked. This article explores the potential relationship between SIBO and gastritis.

Understanding SIBO and Gastritis

Small Intestinal Bacterial Overgrowth occurs when there is an abnormal increase in the number and type of bacteria typically found in the colon, but which have migrated into the small intestine. This part of the digestive tract is usually characterized by a relatively low bacterial count. The presence of too many bacteria in the small intestine can interfere with normal digestion and nutrient absorption.

Gastritis is defined as inflammation of the stomach lining. This lining, known as mucosa, normally shields the stomach from digestive acids. Gastritis can manifest as either acute, with a sudden onset and temporary nature, or chronic, developing gradually over time. This inflammation can weaken the stomach’s protective barrier, leading to irritation and discomfort.

Exploring the Connection

The relationship between SIBO and gastritis is complex, involving several mechanisms. SIBO can disrupt the gut microbiome, the balance of microorganisms in the digestive tract. This imbalance can trigger an inflammatory response that extends beyond the small intestine. Bacterial overgrowth in the small intestine can lead to the production of toxins that irritate or damage the stomach lining, contributing to gastritis.

Motility issues can also play a role. Impaired gut motility is a factor in the development of SIBO, as it allows bacteria to linger and multiply in the small intestine. These same motility problems can affect gastric function, making stomach inflammation more likely. Additionally, reduced stomach acid, known as hypochlorhydria, can predispose individuals to SIBO by allowing bacteria to pass through the stomach more easily. Prolonged use of acid-blocking medications, which reduce stomach acid, can also create conditions where certain bacteria thrive, influencing the gut environment.

Recognizing Symptoms

Both SIBO and gastritis can present with a range of digestive symptoms that often overlap, making them challenging to distinguish without proper evaluation. Common symptoms shared by both conditions include abdominal pain or discomfort, bloating, nausea, and a feeling of fullness after eating.

Gastritis often causes upper abdominal pain, often described as a burning or gnawing sensation, which may improve or worsen after eating. SIBO frequently causes symptoms including excessive gas, abdominal distension, and changes in bowel habits, including diarrhea or constipation. The gas production in SIBO results from bacteria fermenting carbohydrates in the small intestine, leading to pressure and discomfort.

Diagnosis and Treatment Approaches

Diagnosing SIBO and gastritis often involves specific tests. For SIBO, breath tests are a common non-invasive method. These tests measure hydrogen and/or methane levels in the breath after consuming a sugar solution, indicating bacterial fermentation.

Gastritis diagnosis typically involves an examination of the stomach lining. An upper endoscopy allows visual inspection and biopsy. Tests for Helicobacter pylori (H. pylori) infection, a common cause of gastritis, may also be performed using breath, stool, or blood samples.

Treatment for SIBO often includes antibiotics to reduce bacterial overgrowth. Dietary adjustments, such as a low-FODMAP diet or an elemental diet, may also be recommended to manage symptoms. For gastritis, treatment focuses on reducing stomach acid with medications like proton pump inhibitors or H2 blockers, and antibiotics if an H. pylori infection is present. Lifestyle modifications, such as avoiding alcohol and certain irritants, are also important for symptom management.