Does Hydroxyzine Cause Constipation?

Hydroxyzine, often known by brand names like Atarax and Vistaril, is a medication primarily used to manage symptoms of anxiety, alleviate itchiness associated with allergies, and sometimes induce sedation before medical procedures.

Understanding Hydroxyzine and Constipation

Hydroxyzine can cause constipation due to its anticholinergic properties, which block the action of acetylcholine. Acetylcholine stimulates muscle contractions in the digestive system, essential for normal bowel movement. When inhibited, gastrointestinal motility slows. This reduced muscle activity can lead to stools becoming harder and more difficult to pass, resulting in constipation. Hydroxyzine is a first-generation antihistamine; its mild affinity for muscarinic acetylcholine receptors contributes to these anticholinergic effects. While constipation is a possible side effect, it is generally mild for most individuals.

Strategies for Managing Constipation

Several strategies can help manage constipation caused by hydroxyzine. Increasing dietary fiber intake is recommended, as fiber adds bulk to stool and helps it retain water, making it softer and easier to pass. Incorporating more fruits, vegetables, whole grains, nuts, seeds, and legumes into your diet can be beneficial. Prunes, for example, are known for their natural laxative effect due to their fiber and sorbitol content.

Ensuring adequate hydration is equally important, especially when increasing fiber intake, as fiber absorbs water. Drinking plenty of fluids, such as 8 to 10 glasses of water daily, helps soften stools and promotes smoother bowel movements. Limiting excessive caffeine and alcohol consumption may also be helpful, as these can contribute to dehydration. Engaging in regular physical activity supports normal bowel function by stimulating intestinal motility. Even gentle exercises, like daily walks, can make a positive difference.

Over-the-counter options can also provide relief, but consult a healthcare professional before using them, particularly if taking other medications. Stool softeners, such as docusate sodium, work by allowing more water and fat to integrate into the stool, making it softer. Osmotic laxatives, like polyethylene glycol or magnesium hydroxide, draw water into the intestines to soften stool and facilitate its passage. While bulk-forming laxatives are an option, adequate fluid intake is crucial when using them.

When to Seek Medical Advice

While constipation from hydroxyzine is often manageable with lifestyle adjustments and over-the-counter remedies, certain symptoms warrant medical attention. Contact a doctor if you experience severe or worsening abdominal pain, which could indicate a more serious issue. Persistent constipation lasting several days despite home remedies should also be evaluated.

Other concerning signs include blood in the stool, unexplained weight loss, or persistent vomiting alongside constipation. If constipation significantly impacts your quality of life, or if you notice new and unusual changes in your bowel habits, seeking medical advice is prudent. Never adjust your hydroxyzine dosage or discontinue the medication without guidance from your healthcare provider.