Does Hormone Replacement Therapy Stop Periods?

Hormone Replacement Therapy (HRT) addresses symptoms experienced during the menopausal transition. Many individuals wonder about its impact on menstrual cycles. Understanding how HRT interacts with the body’s hormones is important for managing expectations regarding bleeding patterns. This article explores how different HRT regimens influence whether periods continue, change, or cease.

What is Hormone Replacement Therapy

Hormone Replacement Therapy supplements the body with hormones that decrease during menopause. Its purpose is to alleviate menopausal symptoms like hot flashes, night sweats, and vaginal dryness, which result from declining hormone levels. HRT typically involves estrogen and progesterone; estrogen addresses symptoms, and progesterone safeguards the uterine lining. These hormones can be administered as pills, patches, gels, sprays, or vaginal rings.

How HRT Affects Menstrual Cycles

HRT influences menstrual cycles by introducing external hormones. Estrogen thickens the uterine lining, while progesterone stabilizes and triggers its shedding. Consistent HRT hormone levels can change bleeding patterns.

For individuals who have completed menopause, consistent HRT can lead to the cessation of uterine bleeding. A steady hormone supply maintains a stable uterine lining, preventing the cyclical buildup and shedding of a period. If estrogen is given without progesterone in individuals with a uterus, it risks uterine lining overgrowth and cancer.

In perimenopausal individuals, whose natural hormone levels fluctuate, HRT can help regulate cycles. Instead of stopping periods, HRT might make them more predictable or reduce their frequency. It aims to smooth out unpredictable bleeding often experienced during perimenopause.

Different HRT Regimens and Bleeding

The effect of HRT on bleeding patterns depends on the specific regimen. Combined HRT, including both estrogen and progesterone, has two main types based on menopausal stage. Estrogen-only HRT is for those without a uterus.

Cyclical HRT, also known as sequential HRT, is for perimenopausal individuals or those recently in menopause. This regimen involves daily estrogen, with progesterone added for 10 to 14 days each cycle. This structured hormone intake causes a regular “withdrawal bleed” each month, similar to a natural period. Periods do not stop with this HRT type, but become more predictable.

Continuous combined HRT is for individuals at least one year past their last natural period. This regimen involves taking both estrogen and progesterone continuously. The goal is to prevent menstrual bleeding by maintaining a consistently thin uterine lining. While aiming to stop periods, some may experience initial irregular or “breakthrough” bleeding as their body adjusts, especially during the first three to six months.

Estrogen-only HRT is for individuals who have had a hysterectomy. Since the uterus is removed, progesterone is not needed to protect the uterine lining. Therefore, individuals on estrogen-only HRT will not experience uterine bleeding.

Navigating Bleeding While on HRT

Understanding expected bleeding patterns on HRT helps manage concerns. With cyclical HRT, regular monthly withdrawal bleeds are normal and anticipated. These bleeds typically occur after the progesterone phase and are often lighter than natural periods.

For those on continuous combined HRT, initial spotting or irregular breakthrough bleeding is common during the first three to six months as the body adapts. This bleeding usually subsides over time, with many experiencing no bleeding after six months to a year.

Consult a healthcare provider about certain bleeding patterns. This includes persistent or heavy breakthrough bleeding, or any bleeding that starts after a long period of no bleeding on continuous combined HRT. Bleeding on estrogen-only HRT is unexpected and should also be investigated. Any bleeding outside the usual pattern on sequential HRT or any concerning bleeding persisting beyond the initial adjustment period warrants medical advice.