Aleve, known by its active ingredient naproxen sodium, is a common over-the-counter medication used to manage pain and reduce fever. It belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Aleve helps lower a fever, providing relief for individuals with elevated body temperatures. Its effectiveness stems from its action within the body.
How Aleve Reduces Fever
Aleve works by targeting chemical processes in the body that contribute to fever. It temporarily blocks the production of substances called prostaglandins. Prostaglandins are naturally occurring chemicals in the body that play a direct role in triggering pain, inflammation, and fever.
Naproxen, the active ingredient in Aleve, inhibits cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. These enzymes are responsible for synthesizing prostaglandins. By reducing prostaglandin levels, Aleve helps to reset the body’s temperature regulation, thereby bringing down a fever. The effects of Aleve typically begin within 30 to 60 minutes after taking a dose.
Proper Usage for Fever Relief
Adults and children 12 years and older should take one 220 mg caplet every 8 to 12 hours for fever relief, as long as symptoms persist. For faster relief, an initial dose of two caplets (440 mg) can be taken within the first hour. Do not exceed two caplets in any 8- to 12-hour period.
The maximum daily dose is three caplets (660 mg) within 24 hours. Take each dose with a full glass of water. To minimize stomach upset, take Aleve with food or milk. Always consult the product label. Do not use Aleve for fever for more than three days unless advised by a doctor.
Safety and When to Consult a Doctor
Aleve is effective, but be aware of potential side effects and safety considerations. Common side effects include heartburn, nausea, stomach pain, headache, dizziness, or mild rashes. More serious risks associated with NSAIDs like Aleve include gastrointestinal ulcers or bleeding, which can occur without warning and may be life-threatening, particularly in older adults or those using blood thinners.
Aleve can also increase blood pressure, worsen existing heart conditions, and elevate the risk of heart attack or stroke, especially with long-term or high-dose use. Kidney damage can occur, particularly in individuals with pre-existing kidney problems. Avoid Aleve if you have a history of allergic reactions to aspirin or other NSAIDs.
Pregnant women, especially after 20 weeks gestation, should avoid Aleve due to risks to the unborn baby, including kidney problems and issues with heart blood vessels. It is also not recommended for breastfeeding women, and those trying to conceive should know it may affect fertility.
Seek medical attention if a fever worsens or lasts longer than three days, even with Aleve use. Consult a doctor if new or severe symptoms appear, such as signs of stomach bleeding (vomiting blood, black stools), chest pain, shortness of breath, unexplained swelling, or changes in urination. If pain persists for more than 10 days, medical advice is recommended.